Results 61 to 70 of about 994,234 (297)

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Improvements in the Sample Space for the Backscattering Silicon Spectrometer (BASIS)

Quantum Beam Science
The increase in neutron flux at the Oak Ridge National Laboratory (ORNL) Spallation Neutron Source (SNS), currently operating at 2.0 MW proton beam power, has created new opportunities for higher-throughput neutron scattering experiments while also ...
Chris Schmitt, Niina Jalarvo, Naresh C. Osti, Tyler White, John Wenzel, Xiaosong Geng, Rebecca Mills, Eugene Mamontov   +7 more
doaj   +1 more source

Evaluation of the Trapped Surface Wave of a Vertical Electric Dipole Based on Undetermined Coefficient Method in the Presence of N-Layered Region: A Graphical Approach

International Journal of Antennas and Propagation, 2019
In previous studies, the trapped surface wave, which is defined by the residue sums, has been addressed in the evaluation of the Sommerfeld integrals describing electromagnetic field of a vertical dipole in the presence of three-layered or four-layered ...
Hong Lei Xu, Ting Ting Gu, Yong Zhu, Xiao Wei, Liang Sheng Li, Hong Cheng Yin   +5 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

A weak scattering model for tone haystacking

, 2009
The scattering of sound by turbulence in a jet shear layer is considered. Spectral broadening or 'haystacking' is the process whereby the turbulent, time-varying inhomogeneities in the flow scatter tonal sound fields, which decreasesthe level of the ...
Alan McAlpine, Christopher Powles, Tester, B.J., McAlpine, A., Powles, C.J., Brian Tester   +5 more
core   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Seismic wave scattering in volcanoes

, 2008
Volcano-tectonic (VT) earthquakes produce high-frequency seismograms characterized by impulsive shear mech- anism; their seismogram coda re ects the random inhomogeneity of the volcano structure.
Del Pezzo, E.
core   +2 more sources

A Fast Algorithm for Establishing 3-D Scattering Center Model for Ship Targets over Sea Surface Using the Shooting and Bouncing Ray Technique

Leida xuebao, 2019
Fast construction of the 3-D scattering centers of ship targets on the sea surface is important for many radar applications, including the fast signature prediction, feature extraction, and automatic recognition of targets.
YAN Hua, CHEN Yong, LI Sheng, HU Liping, LI Huanmin, YIN Hongcheng   +5 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Linewidths in bound state resonances for helium scattering from Si(111)-(1x1)H [PDF]

, 2009
Helium-3 spin-echo measurements of resonant scattering from the Si(111)–(1 × 1)H surface, in the energy range 4–14 meV, are presented. The measurements have high energy resolution yet they reveal bound state resonance features with uniformly broad ...
Ellis, J., Hedgeland, H., Alexandrowicz, G., Knowling, J., Jardine, A.P., Allison, W., Tuddenham, F.E., Gil Alexandrowicz, MacLaren, D.A.   +8 more
core   +1 more source