Results 161 to 170 of about 1,335,649 (315)

Structural elucidation of the haptoglobin-hemoglobin clearance mechanism by macrophage scavenger receptor CD163. [PDF]

PLoS Biol
Huang CS, Wang H, White JBR, Degtjarik O, Huynh C, Brannstrom K, Horn MT, Muench SP, Somers WS, Chaparro-Riggers J, Lin L, Mosyak L.   +11 more
europepmc   +2 more sources

Polydopamine Nanoparticle‐Mediated Precise Near‐Infrared Optical Stimulation for Cognitive Enhancement

Advanced Science, EarlyView.
Polydopamine nanoparticles enable a precise, non‐genetic, and transcranial neuromodulation strategy via near‐infrared photothermal stimulation. By activating TRPV1 channels, this approach specifically enhances hippocampal gamma oscillations, thereby rescuing spatial memory deficits in models of perioperative neurocognitive disorder.
Yan‐Bo Zhou, Qiong Xue, Su‐Xuan Hou, Ke‐Yao Zhang, Wei‐Tong Pan, Ting‐Ting Zeng, Yu‐Ge Wang, Daqing Ma, Chenguang Zhao, Pan‐Miao Liu, Jian‐Jun Yang   +10 more
wiley   +1 more source

Exploring scavenger receptor class F member 2 and the importance of scavenger receptor family in prediagnostic diseases. [PDF]

Toxicol Res, 2023
Vo TT, Kong G, Kim C, Juang U, Gwon S, Jung W, Nguyen H, Kim SH, Park J.   +8 more
europepmc   +1 more source

TPI1 Loss Triggers a Metabolite‐Driven Mitochondrial Redox Vulnerability via the SARM1–cADPR–Ca2+ Axis

Advanced Science, EarlyView.
Metabolite‐driven redox stress governs cancer cell senescence. TPI1 deficiency elevates DHAP, initiating SARM1‐dependent cADPR‐Ca2+ release. Mitochondrial ROS surge subsequently induces DNA damage and senescence, offering a conserved therapeutic target in multiple cancers.
Chunyu Liu, Shun Wu, Chuang Wang, Zirui Zhou, Tianwei Cai, Wen Tao, Shidong Zuo, Chi Zhang, Yuhao Dong, Yi Feng, Qingbo Huang, Baojun Wang, Xin Ma, Haoli Ma, Xu Zhang, Yan Huang   +15 more
wiley   +1 more source

Scavenger receptor class B type I (SR-BI) as a potential therapeutic target in multiple myeloma [PDF]

Yoshihiko Kondo, Hiromu Yano, Yukio Fujiwara, Daisuke Niino, Yawara Kawano, Jun‐ichirou Yasunaga, Masahiro Yamamoto, Yoshihiro Komohara   +7 more
openalex   +1 more source

Disrupting Helicobacter pylori Iron Homeostasis With Bismuth Nanodrug‐Mediated Nutritional Trap for Targeted Gastric Infection Therapy

Advanced Science, EarlyView.
A “nutritional trap” strategy centered on disrupting bacterial iron homeostasis is proposed. The synthesized Bi‐TP@FU (TBF) can target Helicobacter pylori, interfere with the bacterial iron uptake and utilization processes to disrupt its iron homeostasis, induce bacterial death, and meanwhile preserve the balance of the intestinal flora.
Tianye Fang, Jinzhe Tong, Feng Feng, Cong Liu, Chang Shu, Jiaying Zhu, Shibo Zhang, Shuyue Deng, Wanchao Zuo, Yuhan Song, Jun Yang, Yanmin Ju, Yingying Xing, Jianjun Dai   +13 more
wiley   +1 more source

Facet‐Dependent Activity of Fe3S4 Crystal in Peroxydisulfate Activation for Organic Pollutants Degradation

Advanced Science, EarlyView.
Fe3S4 crystal with the exposed [001] facet exhibits higher catalytic activity for activating peroxydisulfate (PDS) to degrade clothianidin (CLO), which can be attributed to the dissolved Fe‐induced homogeneous catalytic process; while Fe3S4 crystal with the exposed [1‐21] facet exhibits excellent catalytic stability and durability, thereby boosting the
Jiaqu Tan, Min Yu, Jinfeng Wang, Dongya Li, Fan Yang, Yulong Zhang, Xueming Lin   +6 more
wiley   +1 more source

Multifaceted Immune Effects of the Scavenger Receptor CD36 on Long‐Term Outcomes After Neonatal Arterial Focal Stroke

Elena Di Martino, Aditya Rayasam, Amin Mottahedin, Joel Faustino, Shivani Mahuvakar, Carl Joakim Ek, Carina E. Mallard, Zinaida S. Vexler   +7 more
openalex   +1 more source

Synchronized Imaging of Hydrogen Peroxide and Hydroxyl Radical in Pyroptosis and Epilepsy

Advanced Science, EarlyView.
A dual‐responsive fluorescent probe, HH, enables synchronized visualization of H2O2 and •OH through spectrally resolved green and red channels. By tracking redox dynamics in pyroptosis and epilepsy models, HH reveals ROS elevation during seizure‐like pathology and supports evaluation of antioxidant and antiepileptic therapeutic interventions.
Yabing Gan, Yuling Xu, Ting Yu, Yang Li, Xin Jiang, Haoyu Jin, Haitao Li, Youyu Zhang, Peng Yin, Jong Seung Kim   +9 more
wiley   +1 more source

Regulation of lipid oxidation and ferroptosis by a tunable axis of vitamin E, high-density lipoprotein, and scavenger receptor class B type 1

Jonathan Scott Rink, Andrea E. Calvert, Sophia M. Lamperis, Alexandra Moxley, Adam Yuh Lin, SonBinh T. Nguyen, Leo I. Gordon, Colby Shad Thaxton   +7 more
openalex   +1 more source