Results 191 to 200 of about 129,862 (304)

ROS Self‐Supply Nanoplatform Based on Fenton Catalyst for Chemodynamic and Immunotherapy: Reprogramming Cold Tumor Into Hot Tumor in Cancer Treatment

Advanced Science, EarlyView.
A multifunctional HA‐conjugated nanoplatform (HA‐PGMC) integrates CuO2, glucose oxidase, and mil‐100 to enable cascade catalytic ROS generation in tumor microenvironments. This self‐supplying ROS strategy induces immunogenic cell death, reprograms “cold” tumors into “hot” ones, and synergizes with PD‐L1 blockade, achieving potent chemodynamic ...
Man Lung Lee, Jack Chun Hin Chen, Wai Wing Cheng, Kwan Yee Lau, Hiu Yee Kwan, Ngar‐Yun Ellen Poon, Hung‐Wing Li   +6 more
wiley   +1 more source

Iron-dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP-1 monocytes. [PDF]

FEBS Open Bio
Čierna M, Buchal R, Leníček M, Shachak A, Pláteník J.   +4 more
europepmc   +1 more source

Scavenger receptor A-mediated nanoparticles target M1 macrophages for acute liver injury. [PDF]

Asian J Pharm Sci, 2023
Zhang R, Luo S, Zhao T, Wu M, Huang L, Zhang L, Huang Y, Gao H, Sun X, Gong T, Zhang Z.   +10 more
europepmc   +1 more source

Microglia‐Targeted Biomimetic Tetrahedral Framework Nucleic Acid Nanovesicles for Synergistic Treatment of Sepsis‐Associated Encephalopathy

Advanced Science, EarlyView.
Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi, Qiuxia Gao, Wenying Wang, Bin Li, Yukun Chen, Zhijun Yao, Yujie Li, Junrui Li, Na Li, Gong Gu, Zhimin Hou, Mengyuan Yang, Ruilin Zhang, Hongju Yang, Yuhui Liao, Hongyi Lei   +15 more
wiley   +1 more source

Retraction Note: Superparamagnetic iron oxide nanoparticles conjugated with Aβ oligomer-specific ScFv antibody and class A scavenger receptor activator show therapeutic potentials for alzheimer's disease. [PDF]

J Nanobiotechnology
Liu XG, Zhang L, Lu S, Liu DQ, Huang YR, Zhu J, Zhou WW, Yu XL, Liu RT.   +8 more
europepmc   +1 more source

Retraction notice to "Deletion of the scavenger receptor Scarb1 in myeloid cells does not affect bone mass" [Bone 170(2023) 116702]. [PDF]

Bone, 2023
Palmieri M, Joseph TE, O'Brien CA, Gomez-Acevedo H, Kim HN, Manolagas SC, Ambrogini E.   +6 more
europepmc   +1 more source

Tetrahedral DNA Nanostructure‐Based Biomimetic Nanovesicles Attenuate Sepsis‐Associated ARDS by Suppressing Glycolysis via the BMAL1/PFKFB3 Axis

Advanced Science, EarlyView.
Upon inhalation, RM@TNT could persist long‐term in the diseased lungs, while undergoing disintegration to release TNT specifically within the ROS‐rich pathological microenvironments of SA‐ARDS. The released TNT was then precisely delivered to AMs via Tuftsin, where it released Nob intracellularly to activate BMAL1 expression, thus inhibiting AM ...
Yunlong Zhang, Bin Li, Zhijin Fan, Yan Yan, Fei Ma, Changting He, Shiping Liu, Mingliang Pan, Zhou Pan, Huijuan Wang, Xinting Fu, Jiamei Wang, Yue Jia, Qin Gu, Duo Jiang, Xueting Liu, Bohua Ren, Qinqin Wang, Yuehua Hei, Han Duan, Yanqiu Wu, Zihui Wei, Liying Zhan, Yuhui Liao   +23 more
wiley   +1 more source

The potential role of scavenger receptor B type I (SR-BI) in SARS-CoV-2 infection. [PDF]

Immun Inflamm Dis, 2023
Alkazmi L, Al-Kuraishy HM, Al-Gareeb AI, Alexiou A, Papadakis M, Saad HM, Batiha GE.   +6 more
europepmc   +1 more source

Mitochondrial Enzymes Mimetic Ultrasmall Palladium Nanozymes Prevent Senescence and Neurodegeneration Through Metabolic Reprogramming

Advanced Science, EarlyView.
Simply constructed polyvinylpyrrolidone (PVP) modified palladium nanoparticles (PdP NPs) as cytochrome c oxidase (CcO) and superoxide dismutase (SOD) mimic are promising multifunctional nanoreactors to boost mitochondrial respiration chain function and refine homeostasis via regulation of mitochondrial dynamics and proteostasis sensor UPRmt, which ...
Wenshu Cong, Haiming Jing, Zinan Li, Wenjing Zhang, Nan Zhang, Yingqiu Xie, Shan Gao, Yuanyu Huang, Junyu Ning   +8 more
wiley   +1 more source

Structure of scavenger receptor SCARF1 and its interaction with lipoproteins. [PDF]

Elife
Wang Y, Xu F, Li G, Cheng C, Yu B, Zhang Z, Kong D, Chen F, Liu Y, Fang Z, Cao L, Yu Y, Gu Y, He Y.   +13 more
europepmc   +1 more source