Functional LCAT deficiency in human apolipoprotein A-I transgenic, SR-BI knockout mice
Reduction of plasma LCAT activity has been observed in several conditions in which the size of HDL particles is increased; however, the mechanism of this reduction remains elusive. We investigated the plasma activity, mass, and in vivo catabolism of LCAT
Lee Ji-Young+6 more
doaj
Bayesian Density-Density Regression with Application to Cell-Cell Communications [PDF]
We introduce a scalable framework for regressing multivariate distributions onto multivariate distributions, motivated by the application of inferring cell-cell communication from population-scale single-cell data. The observed data consist of pairs of multivariate distributions for ligands from one cell type and corresponding receptors from another ...
arxiv
Lutein transport by Caco-2 TC-7 cells occurs partly by a facilitated process involving the scavenger receptor class B type I (SR-BI) [PDF]
Emmanuelle Reboul+9 more
openalex +1 more source
This work summarizes the efficacy and mechanisms of probiotics in CRC treatment, providing a comprehensive overview of various encapsulation methods such as microcapsules, hydrogels, single‐cell nanocoatings, and nanofibers for targeted probiotic delivery to inflammatory sites, with particular emphasis on the potential advantages of emerging single ...
Hao Zhong+5 more
wiley +1 more source
HDL-mediated cholesterol uptake and targeting to lipid droplets in adipocytes
Adipocytes express high levels of the HDL scavenger receptor class B type I in a differentiation-dependent manner. We thus have analyzed the routes of HDL cholesterol trafficking at different phases of adipocyte differentiation in the 3T3-L1 cell line ...
Georges Dagher+4 more
doaj
A Polymorphism Exon 1 Variant at the Locus of the Scavenger Receptor Class B Type I (SCARB1) Gene Is Associated with Differences in Insulin Sensitivity in Healthy People during the Consumption of an Olive Oil-Rich Diet [PDF]
Pablo Pérez‐Martínez+9 more
openalex +1 more source
This study uncovers that CD38high monocytes discriminate sepsis and sterile inflammation and are associated with 28‐day mortality in bacterial sepsis. Targeting CD38 therapy reduces inflammatory response in monocytes and in sepsis mice model. Mechanistically, CD38‐HIF‐1α/glycolysis/MGO loop exacerbates sepsis‐induced immune dysregulation.
Ning Hua+19 more
wiley +1 more source
High scavenger receptor class B type I expression is related to tumor aggressiveness and poor prognosis in lung adenocarcinoma: A STROBE compliant article. [PDF]
Feng H+6 more
europepmc +1 more source
The scavenger receptor class B type I (SR-BI), which is expressed in the liver and intestine, plays a critical role in cholesterol metabolism in rodents.
Pablo Mardones+11 more
doaj
Association of lower plasma estradiol levels and low expression of scavenger receptor class B, type I in infertile women [PDF]
Maria Velasco+5 more
openalex +1 more source