Results 211 to 220 of about 103,100 (354)

Bionic Microneedle Patch Inspired by Drosophila Tarsal Paws Boosts Healing in Bacterial Infectious Stomatitis

Advanced Science, EarlyView.
Microneedle suction cup patches, prepared using bionic Drosophila tarsal claws, can effectively treat bacterial infectious stomatitis by rapidly and efficiently leveraging multiple effects, including antibacterial and anti‐inflammatory properties, promotion of vasodilation, and active mechanical contraction of the wound.
Jiaqi Qin, Cewen Hu, Xiaohong Ran, Huajing Zeng, Jie Zhang, Bin Liu, Zengjie Fan   +6 more
wiley   +1 more source

Hepatic cholesterol and bile acid metabolism and intestinal cholesterol absorption in scavenger receptor class B type I-deficient mice

Journal of Lipid Research, 2001
The scavenger receptor class B type I (SR-BI), which is expressed in the liver and intestine, plays a critical role in cholesterol metabolism in rodents.
Pablo Mardones, Verónica Quiñones, Ludwig Amigo, Mauricio Moreno, Juan Francisco Miquel, Margrit Schwarz, Helena E. Miettinen, Bernardo Trigatti, Monty Krieger, Sonya VanPatten, David E. Cohen, Attilio Rigotti   +11 more
doaj  

High scavenger receptor class B type I expression is related to tumor aggressiveness and poor prognosis in lung adenocarcinoma: A STROBE compliant article. [PDF]

Medicine (Baltimore), 2018
Feng H, Wang M, Wu C, Yu J, Wang D, Ma J, Han J.   +6 more
europepmc   +1 more source

The inhibition of endocytosis affects HDL-lipid uptake mediated by the human scavenger receptor class B type I [PDF]

, 2007
Yi Zhang, Ayesha Ahmed, Thu L. Tran, Judy Lin, Nicole McFarlane, Douglas R. Boreham, Suleiman A. Igdoura, Ray Truant, Bernardo L. Trigatti   +8 more
openalex   +1 more source

Mechanical Biomimetic Nanocomposites for Multidimensional Treatment of Arterial Thrombosis

Advanced Science, EarlyView.
In this study, a mechanical biomimetic nanocomposite is developed, guided by photoacoustic imaging, to achieve highly efficient and safe thrombolysis through the synergistic effects of photothermal therapy and pharmacological intervention. Most notably, the nanoparticle improves the microenvironment of arterial thrombi, marked by high shear stress and ...
Ying Li, Qi Xiang, Yan Zhang, Fuxue Luo, Yunfang Wu, Haitao Ran, Yang Cao   +6 more
wiley   +1 more source

Intestinal SR-BI does not impact cholesterol absorption or transintestinal cholesterol efflux in mice

Journal of Lipid Research, 2013
Reverse cholesterol transport (RCT) can proceed through the classic hepatobiliary route or through the nonbiliary transintestinal cholesterol efflux (TICE) pathway.
Kanwardeep S. Bura, Caleb Lord, Stephanie Marshall, Allison McDaniel, Gwyn Thomas, Manya Warrier, Jun Zhang, Matthew A. Davis, Janet K. Sawyer, Ramesh Shah, Martha D. Wilson, Arne Dikkers, Uwe J.F. Tietge, Xavier Collet, Lawrence L. Rudel, Ryan E. Temel, J.Mark Brown   +16 more
doaj  

Variants in Scavenger Receptor Class B Type I Gene Are Associated with HDL Cholesterol Levels in Younger Women [PDF]

, 2007
Caroline G. P. Roberts, Haiqing Shen, Braxton D. Mitchell, Coleen Damcott, Alan R. Shuldiner, Annabelle Rodríguez   +5 more
openalex   +1 more source

Sortilin‐Mediated Rapid, Precise and Sustained Degradation of Membrane Proteins via mRNA‐Encoded Lysosome‐Targeting Chimera

Advanced Science, EarlyView.
The study identified sortilin as a promising LTR, enabling targeted degradation of oncogenic proteins through an mRNA‐encoded MedTAC strategy. In a mouse model, MedTACPTK7 reduced PTK7 by up to 80%, extended survival, and showed excellent pharmacokinetics without toxicity, providing a scalable platform for targeted therapies.
Xin Chang, Xinyu Qiu, Xiaoning Tong, Shaoju Gan, Weicheng Yi, Sitao Xie, Xiangsheng Liu, Chao Zuo, Weihong Tan   +8 more
wiley   +1 more source

Secretory phospholipase A2 increases SR-BI-mediated selective uptake from HDL but not biliary cholesterol secretions⃞

Journal of Lipid Research, 2008
High density lipoprotein cholesterol represents a major source of biliary cholesterol. Secretory phospholipase A2 (sPLA2) is an acute phase enzyme mediating decreased plasma HDL cholesterol levels. Clinical studies reported a link between increased sPLA2
Uwe J.F. Tietge, Niels Nijstad, Rick Havinga, Julius F.W. Baller, Fjodor H. van der Sluijs, Vincent W. Bloks, Thomas Gautier, Folkert Kuipers   +7 more
doaj  

Class B type I scavenger receptor is responsible for the high affinity cholesterol binding activity of intestinal brush border membrane vesicles [PDF]

, 2007
Eric D. Labonté, Philip N. Howles, Norman A. Granholm, Juan Camilo Rojas Echeverri, Joanna P. Davies, Yiannis A. Ioannou, David Y. Hui   +6 more
openalex   +1 more source