Results 121 to 130 of about 20,627 (152)

SR-B1-Mediated Transplacental Transfer of Hydrophobic Toxicants Disrupts Fetal Development During Barriergenesis. [PDF]

Adv Sci (Weinh)
Huang Y, Shang H, Jiao L, Chen C, Liu Z, Yang Y, Zhang Q, Tang S, Jia X, Yang H, Wan Y.   +10 more
europepmc   +1 more source

Narcissoside attenuates atherosclerosis by suppressing CD36-mediated foam cell formation via upregulation of NR4A1. [PDF]

Chin Med
Wang Z, Zhou L, Zhang X, Yao Z, Huang Y, Wang L, Pan K, Zhang J, Zhi H, Yin Z.   +9 more
europepmc   +1 more source

Lipid droplets in the tumor microenvironment: Biogenesis, functional diversity, and therapeutic targeting. [PDF]

Chin Med J (Engl)
Zhong J, Liu Y, Wang C, Li S, Bian XW, Ping YF.   +5 more
europepmc   +1 more source

Recent insights into the pathophysiology and implications for surgery in atherosclerosis. [PDF]

J Cardiothorac Surg
Liu L, Wang Z, Ma L, Wu S.
europepmc   +1 more source

Scavenger Receptor Class B Type I Regulates Plasma Apolipoprotein E Levels and Dietary Lipid Deposition to the Liver

Biochemistry, 2015
Scavenger receptor class B type I (SR-BI) is primarily responsible for the selective uptake of cholesteryl esters (CE) of high-density lipoprotein (HDL) by the liver and other tissues. In the present study, we show that SR-BI-deficient (scarb1(-/-)) mice are resistant to diet-induced obesity, hepatic lipid deposition, and glucose intolerance after 24 ...
Eleni A, Karavia, Nikolaos I, Papachristou, George C, Sakellaropoulos, Eva, Xepapadaki, Eleni, Papamichail, Peristera-Ioanna, Petropoulou, Eugenia P, Papakosta, Caterina, Constantinou, Ioannis, Habeos, Dionysios J, Papachristou, Kyriakos E, Kypreos   +10 more
openaire   +2 more sources

Effects of β3-adrenoceptor on scavenger receptor class B type 1 and its signal transduction pathway in apolipoprotein E knockout mice

European Journal of Pharmacology, 2013
It is clear that activated β3-adrenoceptor can improve disorders of lipid metabolism, however there are few reports concerning the anti-atherosclerotic effects of β3-adrenoceptor in the artery of apolipoprotein E knockout (Apoe−/−) mice. In the present study, we aimed at investigating the effects of β3-adrenoceptor on lipids, atherosclerosis plaques ...
Yan-qing Guo, Yan-fang Li, Zhao-hong Wang   +2 more
openaire   +1 more source

Abstract 187: Genetic Targeting at Apolipoprotein E Locus to Knockdown Scavenger Receptor Class B Type I in Mice: Characterization of a Novel Mouse Model of Coronary Heart Disease

Arteriosclerosis, Thrombosis, and Vascular Biology, 2017
Background: Scavenger Receptor Class B Type I (SRBI) is the key player mediating HDL-dependent reverse cholesterol transport (RCT) in hepatocyte, and SRBI mutation causes coronary heart disease (CHD) in humans. Mice lacking SRBI and apolipoprotein E (apoE), fed on chow diet, develop cardinal features of CHD and succumb to ...
Hong Chen, Sheng Hu, Xing Y Huo, Li Y Zhu, Qing Wan, Xiao Y Ma, Chuan S Xu, Hui F Hao, Wei J Jin, Miao Wang   +9 more
openaire   +1 more source

Abstract 2824: Physiologic regulation of lipid oxidation and ferroptosis by vitamin E, high-density lipoprotein and scavenger receptor class B type 1

Cancer Research
Abstract Introduction: Ferroptosis is a form of cell death caused by oxidative (-OOH) damage to phospholipids (PL) in the cell membrane. Understanding mechanisms of ferroptosis is important because of the role it plays in cancer.
Jonathan S. Rink, Andrea E. Calvert, Adam Y. Lin, SonBihn T. Nguyen, Leo I. Gordon, C Shad Thaxton   +5 more
openaire   +1 more source

Effects of β₃-adrenoceptor on scavenger receptor class B type 1 and its signal transduction pathway in apolipoprotein E knockout mice.

European journal of pharmacology, 2014
It is clear that activated β₃-adrenoceptor can improve disorders of lipid metabolism, however there are few reports concerning the anti-atherosclerotic effects of β₃-adrenoceptor in the artery of apolipoprotein E knockout (Apoe(-/-)) mice. In the present study, we aimed at investigating the effects of β₃-adrenoceptor on lipids, atherosclerosis plaques,
Yan-qing, Guo, Yan-fang, Li, Zhao-hong, Wang   +2 more
openaire   +1 more source