Results 51 to 60 of about 20,627 (152)

ANALYSIS OF CELLULAR SENTINELS FOR EXTRACELLULAR HEAT SHOCK PROTEIN-PEPTIDE COMPLEXES [PDF]

, 2013
Since the discovery of gp96 in the 1980’s as a “tumor rejection antigen,” Heat Shock Proteins (HSPs) have received attention from immunologists for their ability to prime immune responses.
Messmer, Michelle
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Structure-Activity Relationship of PEGylated Polylysine Peptides as Scavenger Receptor Inhibitors for Non-Viral Gene Delivery

, 2015
PEGylated polylysine peptides of the general structure PEG30 kDa-Cys-Trp-LysN (N = 10 to 30) were used to form fully condensed plasmid DNA (pGL3) polyplexes at a ratio of 1 nmol of peptide per μg of DNA (ranging from N:P 3:1 to 10:1 depending on Lys ...
Khargharia S., Crowley S. T., Allen R. J., Duskey J. T., White C. W., Baumhover N. J., Rice K. G.   +6 more
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Hepatitis C virus evasion mechanisms from neutralizing antibodies [PDF]

, 2011
Hepatitis C virus (HCV) represents a major public health problem, affecting 3% of the world’s population. The majority of infected individuals develop chronic hepatitis, which can progress to cirrhosis and hepatocellular carcinoma.
Angus, Allan G.N., Arvind H. Patel, Patel, Arvind H., Caterina Di Lorenzo, Allan G. N. Angus, Lorenzo, Caterina D.   +5 more
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Implications of Scavenger Receptors in the Safe Development of Nanotherapeutics

, 2015
Nanomaterials (NMs) are being utilized in a variety of biomedical applications including drug delivery, diagnostics, and therapeutic targeting. These applications are made possible due to the unique physicochemical properties that are exhibited at the ...
Jonathan Shannahan, Wei Bai, Jared Brown
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Lipid metabolism and HCV infection [PDF]

, 2010
Chronic infection by hepatitis C virus (HCV) can lead to severe liver disease and is a global healthcare problem. The liver is highly metabolically active and one of its key functions is to control the balance of lipid throughout the body.
Boulant, Steeve, Paul Targett-Adams, Targett-Adams, Paul, Douglas, Mark W., McLauchlan, John, Steeve Boulant, John McLauchlan, Mark W. Douglas   +7 more
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Structure-binding activity relations of amphiphilic polymers and macrophage scavenger receptors: implications for therapeutic inhibition of atherosclerosis

, 2010
Scavenger receptors mediate the uptake of oxidized low density lipoprotein (oxLDL), leading to cholesterol accumulation and the development of atherosclerosis.
Plourde, Nicole M., 1982-
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The collagenous domain of classA scavenger receptors is involved in macrophage adhesion to collagens

, 2001
Class A macrophage scavenger receptors (MSRs) have a remarkably broadligand specificity and are well‐known for their roles in atherogenesisand host defense.
Borg, T. K., Ghaffar, A., Gowen, Brian B., Mayer, E. P.   +3 more
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Differentiation of the mononuclear phagocyte system during mouse embryogenesis:the role of transcription factor PU.1

, 1999
During mouse embryogenesis, macrophage-like cells arise first in the yolk sac and are produced subsequently in the liver. The onset of liver hematopoiesis is associated with the transition from primitive to definitive erythrocyte production.
Lichanska, A M, Ostrowski, M C, Henkel, G W, Maki, R A, Murphy, K M, Browne, C M, Hume, D A, McKercher, S R   +7 more
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Identification of a Candidate CD5 Homologue in the Amphibian Xenopus laevis [PDF]

, 1995
We identified a novel T cell Ag in the South African clawed toad (Xenopus laevis) by a mAb designated 2B1. This Ag is present in relatively high levels on most thymocytes, approximately 65% of splenocytes, 55% of PBL, and 65% of intestinal lymphocytes ...
Cooper, Max D., Pasquier, Louis D., Göbel, Thomas W. F., Gartland, Lanier A., Jürgens, Jutta B., Horton, John D.   +5 more
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Native high-density lipoproteins inhibit platelet activation via scavenger receptor BI Role of negatively charged phospholipids

, 2011
ObjectivesHIGH-density lipoproteins (HDL) are a negative predictor of platelet-dependent thrombus formation and reduced platelet activation has been observed in vitro in the presence of HDL3, a major HDL fraction.
Kehrel, Beate E., Korporaal, Suzanne J.A., Van Eck, Miranda, Van Berkel, Theo J. C., Manfred Fobker, Nofer, Jerzy-Roch, Van Berkel, Theo J.C., Jerzy-Roch Nofer, Grazyna Herminghaus, Uwe J.F. Tietge, Theo J.C. Van Berkel, Brodde, Martin F., Miranda Van Eck, Tietge, Uwe J. F., Martin F. Brodde, Herminghaus, Grazyna, Tietge, Uwe J.F., Suzanne J.A. Korporaal, Horst Robenek, Beate E. Kehrel, Robenek, Horst, Fobker, Manfred, Korporaal, Suzanne J. A.   +22 more
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