Results 201 to 210 of about 405,215 (310)

Pemt Inhibition‐Mediated Vdac1 Oligomerization Regulates Mitochondrial Dysfunction, Apoptosis, and Inflammation in High‐Fat Diet‐Derived Liver Injury

Advanced Science, EarlyView.
ABSTRACT High‐fat diet (HFD)‐induced hepatic injury represents a pathology observed across vertebrates, yet the underlying mechanisms remain incompletely understood. Herein, the present study identifies phosphatidylethanolamine methyltransferase (Pemt), a key enzyme in phosphatidylcholine synthesis, as a critical regulator of mitochondrial homeostasis ...
Xianyong Bu, Xiufei Cao, Xin Yao, Baolin Li, Wencong Lai, Zengqi Zhao, Tingting Hao, Zhiwei Chen, Jianlong Du, Yueru Li, Kangsen Mai, Qinghui Ai   +11 more
wiley   +1 more source

A high surface area silica-supported aldehyde as a flow-compatible amine scavenger. [PDF]

RSC Adv
Reinhardt AM, Panayides JL, Riley DL.
europepmc   +1 more source

Single‐Cell Reveal GALNT7‐Dependent Ferroptosis Suppression as a Mechanism of Immunotherapy Resistance in Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
Integrated clinical and mechanistic analyses identify GALNT7 as a ferroptosis‐suppressive regulator associated with immunotherapy resistance in non‐small cell lung cancer. GALNT7 depletion promotes lipid peroxidation, mitochondrial dysfunction, and ferroptosis, enhances CD8+ T‐cell activation and IFN‐γ production, and sensitizes tumors to PD‐1 blockade,
Jiadi Gan, Qian Zheng, Deng Liu, Ruichao Nie, Menglin Yao, Xiaolong Tang, Renjie Xu, Jinghong Xian, Wenjun Meng, Wenxin Luo, Dan Liu, Guiyi Ji   +11 more
wiley   +1 more source

Fulvic Acid Suppresses Excessive Cytokinin Biosynthesis to Reduce ROS Content and thus Decrease Na⁺ Accumulation and Toxicity, Enhancing Salt Tolerance in Rice. [PDF]

Rice (N Y)
Zhu Y, Wang Q, Zhang J, Li M, Ma F, Lan Q, Yin C, Lin Y.   +7 more
europepmc   +1 more source

Micro‐Galvanic Coupling Programs the Therapeutic Zinc Ion Window to Reconfigure Immune Cascades for Pro‐Regenerative Bone Healing

Advanced Science, EarlyView.
This study utilized alloy micro‐galvanic coupling design to regulate the release of essential elements, thereby programming immune responses and promoting regeneration. The sacrificial anodic process of Zn‐0.8Mg reduced Zn2+ release compared to the “large cathode‐small anode” coupling of Zn‐0.8Fe.
Chaoyang Sun, Bo Jia, Jiahui Shi, Shuang Li, Guo Bao, Dong Bian, Kai Chen, Junlong Tan, Xuenan Gu, Yan Guan, Yu Qin, Xinhua Qu, Xiaogang Wang, Yufeng Zheng, Hongtao Yang   +14 more
wiley   +1 more source

Partial characterization and evaluation of antioxidant and antibacterial activities of a water soluble polysaccharide isolated from Euphorbia hebecarpa roots. [PDF]

Sci Rep
Juybari EA, Farimani MM, Asadollahi M.
europepmc   +1 more source

Furfuryl Alcohol‐Driven Proton Supply Enables Efficient Photocatalytic H2O2 Production Beyond Water‐Based Systems

Advanced Science, EarlyView.
A ZnIn2S4–carbon dot heterojunction enables photocatalytic H2O2 production coupled with furfuryl alcohol oxidation. In this redox system, furfuryl alcohol acts as both the electron donor and oxidation substrate, producing furoic acid with 100% selectivity and 98% conversion while supporting efficient H2O2 generation with a solar‐to‐chemical conversion (
Pengfei Bai, Ning Li, Quan Zhou, Bin Liu, Xiangqian Fan, Lei Liu, Jingkai Lin, Weijie Ren, Shengliang Hu, Huayang Zhang   +9 more
wiley   +1 more source

Scavenger Assemblage Behavior at Puma Kills in the Santa Cruz Mountains, California. [PDF]

Ecol Evol
Allen ML, Allan ATL, King RM, Warner BH, Morgan JJ, Wilmers CC.   +5 more
europepmc   +1 more source

Inside‐Outside ROS Therapeutic Strategy Based on Piezoelectric Nano‐Urchin for Drug‐Resistant Bacteria Biofilm Infections

Advanced Science, EarlyView.
The contribution of this study lies not only in enabling effective treatment of drug‐resistant biofilm infections, but also in establishing a transferable therapeutic paradigm: Ultrasound‐triggered mechanical forces synergistically enhance piezoelectric polarization and nanozyme activity, driving functional ROS generation inside and outside biofilms ...
Xinjian Guo, Jin Yang, Mengjie An, Bingjie Lin, Tao Liu, Limin Zhang   +5 more
wiley   +1 more source