Results 221 to 230 of about 455,702 (308)

Ammonia Detoxification Inhibits Liver Metastasis by Reshaping Hepatic Microenvironment

Advanced Science, EarlyView.
Liver metastasis diverts aspartate into hyperactive pyrimidine synthesis, disrupting urea cycling and causing pathogenic ammonia accumulation. Ammonia dually reprograms the microenvironment by: (1) activating hepatic stellate cells (HSCs) into pro‐fibrotic metastasis‐associated fibroblasts (MAFs), and (2) suppressing anti‐tumor monocytes/macrophages ...
Sumin Sun, Haili Hu, Long Chen, Yuan Gao, Peng Sun, Liming Chen   +5 more
wiley   +1 more source

Dietary isothiocyanates as redox-active bioactives: A comprehensive review of chemistry. [PDF]

Food Chem (Oxf)
Lu Y.
europepmc   +1 more source

Cascade‐Responsive MXene@Cu‐MOF Heterostructure Integrates Antioxidant Activity, Infection Control, and Vascularization for Tracheal Repair

Advanced Science, EarlyView.
A cascade‐responsive MXene@Cu‐MOF/GelMA hydrogel is engineered as a “skeleton–backpack” platform for extensive tracheal repair. The MXene framework scavenges postoperative ROS and converts NIR light into mild hyperthermia, while the Cu‐MOF component provides pH/NIR‐responsive Cu2+ dosing for infection control, angiogenesis, and chondrogenesis.
Liang Guo, Yingran Shen, Jiaoyu Yi, Juanjuan Li, Ziming Wang, Erji Gao, Siqiang Zheng, Zhe‐Sheng Chen, Bo Tao   +8 more
wiley   +1 more source

Comparative Biofunctionality Assessment of Lignin and Lignin/Chitosan Nanoparticles: Impact of Chitosan Co-Assembly on Cytotoxicity, Cytocompatibility, Radical-Scavenging Activity, and Antimicrobial Performance. [PDF]

Pharmaceutics
Zagorcheva T, Andonova-Lilova B, Georgieva D, Hristova S, Yanev Z, Rusenova N, Beev G, Petkova-Parlapanska K, Nikolova G, Karamalakova Y, Yaneva Z.   +10 more
europepmc   +1 more source

Fe2+‐ Induced Activation of Single and Dual Metal Site—Lattice Oxygen Mechanism in Fe Rich NiFe‐LDHs for Oxygen Evolution Reaction

Advanced Science, EarlyView.
Fe‐rich NiFe‐LDH catalysts derived from MOFs, showing superior OER activity via lattice oxygen mechanism activation. ABSTRACT Developing a durable and efficient oxygen evolution reaction (OER) catalyst without noble metals is essential for the economical and sustainable production of hydrogen by alkaline water electrolysis.
Nithinraj Panangattu Dharmarajan, Mohammed Fawaz, Vanshree Parey, Sudip Chakraborty, CI Sathish, Thi Thuy Kieu Tran, Xuan Minh Chau Ta, Siddulu Naidu Talapaneni, Zhixuan Li, Kavitha Ramadass, Antonio Tricoli, Jae‐Hun Yang, Ajayan Vinu   +12 more
wiley   +1 more source

FASLG Derived from Fibroblasts in Hydroxyapatite‐Rich Microenvironment Induces Urothelial Anoikis to Trigger Randall's Plaque Exposure

Advanced Science, EarlyView.
Randall's plaques (RP) serve as the nidus for calcium oxalate (CaOx) kidney stones. The current study reveals that hydroxyapatite (HAP) crystals activate the THY1–GSK3α/β–β‐catenin axis in renal interstitial fibroblasts (hRIFs), inducing FASLG secretion.
Minghui Liu, Maolan Wu, Meng Gao, Yongchao Li, Miao Yuan, Zhangcheng Liao, Zhi Liu, Yizhou Wang, Yu Cui, Jinbo Chen, Cheng He, Zhiyong Chen, Feng Zeng, Hequn Chen, Zewu Zhu   +14 more
wiley   +1 more source

Phytochemical Profiling and Antioxidant Activity of <i>Justicia thunbergioides</i> (Lindau) Leonard (Acanthaceae): A Promising Source of Therapeutic Metabolites. [PDF]

Pharmaceuticals (Basel)
Provensi LR, Carneiro MRB, Martins-Oliveira A, Porto ALM, Gil ES, Peixoto JC, Rosseto LP.   +6 more
europepmc   +1 more source

Lipoic Acid‐Intervened Decellularized Stem Cell Spheroid‐Based Injectable Granular Gel for Diabetic Tissue Regeneration

Advanced Science, EarlyView.
ABSTRACT Advancements in tissue engineering have revolutionized therapeutic paradigms for diabetic tissue defects; however, the lack of applicable scaffold containing various bioactive substance aggregates remained a critical bottleneck hindering satisfactory repair effect.
Tao Wang, Haowei Fang, Lili Qi, Song Myoungseop, Aawrish Khan, Lunli Gong, Guangdong Zhou, Kunxi Zhang, Haiyan Cui   +8 more
wiley   +1 more source