Results 41 to 50 of about 138,112 (264)

CauFinder: Steering Cell‐State and Phenotype Transitions by Causal Disentanglement Learning

Advanced Science, EarlyView.
CauFinder combines causal disentanglement modeling and network control to prioritize causal drivers of cell‐state transitions from observational transcriptomic data. The framework separates transition‐relevant signals from spurious associations, nominates intervention targets across biological and disease contexts, and identifies DAAM1 as an actionable
Chengming Zhang, Zexi Chen, Yuanxiang Miao, Zuolin Shen, Deyu Cai, Shijie Tang, Yun Xue, Weifeng Guo, Hongbin Ji, Jian Liu, Kazuyuki Aihara, Luonan Chen   +11 more
wiley   +1 more source

Does the Autophagy Related Gene 7 (ATG7) Have a Role in Non-Melanoma Skin Cancer?

Clinical, Cosmetic and Investigational Dermatology, 2020
Rehab M Samaka, 1 Mohammed A Basha, 2 Eman Mansour 3 1Pathology Department, Faculty of Medicine, Menoufia University, Al Minufya, Egypt; 2Dermatology, Andrology and STDs Department, Faculty of Medicine, Menoufia University, Al Minufya, Egypt ...
Samaka RM, Basha MA, Mansour E
doaj  

Mandibular squamous cell carcinoma in a captive Siberian tiger (Panthera tigris altaica)

Brazilian Journal of Veterinary Pathology, 2018
Squamous cell carcinoma (SCC) is a common oral neoplasm in domestic cats, but there are only a few reports in wild felids. A captive 10-years-old, female Siberian tiger (Panthera tigris altaica), with history of chronic renal disease and serologically ...
Ayisa R. de Oliveira, Tatiane F. de Carvalho, Alexandre Arenales, Herlandes P. Tinoco, Carlyle M. Coelho, Maria Elvira L. T. Costa, Tatiane A. Paixão, Eduardo A. Caixeta, Guilherme R. G. Pinheiro, Renato L. Santos   +9 more
doaj   +1 more source

CD177 Deficiency Defines a Stable Subtype of Human Neutrophil Granulocytes with Tumor Promoting Activity

Advanced Science, EarlyView.
Human neutrophils exist as two epigenetically imprinted subtypes defined by stable CD177 expression or absence — a ratio that persists across time, circadian rhythms, and inflammation. CD177− neutrophils display a distinct molecular landscape enriched in arginase 1 and lipid metabolism markers, accumulate in head‐and‐neck tumors, and associate with ...
Marcel Jung, Alexander Beer, Susmita Ghosh, Ekaterina Pylaeva, Belal Alshaar, Tobias Tertel, Nils Bastian Leimkühler, Thomas Schroeder, Janine Gronewold, Nina Hagemann, Ayan Mohamud Yusuf, Benedikt Frank, Yiqiao Zhang, Dennis Nagel, Kim Schloeßer, Laura Karsch, Emily Hedtfeld, Sabrina Lohmann, Kathrin Blank, Andreas Kraus, Max Krumbein, Nastassia Kabankova, Hongxiao Wang, Almke Bader, Mathis Richter, Fengjun Zhang, Raphael Chevre, Bernd Giebel, Stephan Lang, Anika Grüneboom, Daniela Maier‐Begandt, Anja Hasenberg, Oliver Soehnlein, Hans Christian Reinhardt, Sven Heiles, Jianxu Chen, Jadwiga Jablonska, Albert Sickmann, Dirk M. Hermann, Matthias Gunzer   +39 more
wiley   +1 more source

Behavior of RC Beams Under Two Points Load with Different Out-of-Plane Parts

Civil and Environmental Engineering
This study focused on the out-of-plane beam behavior and the reduction caused by changes in the longitudinal axis and the out-of-plane span length in addition to the effect of adding torsion reinforcement.
Muhammed Nura Jasim, Al-Azzawi Adel A.
doaj   +1 more source

PDGFRα+/Integrin α2+ Fibroblasts Orchestrate Tumor Budding in Oral Squamous Cell Carcinoma via Mechano‐Metabolic Symbiosis: E‐Cadherin/Integrin α2β1 Adhesion and Mitochondrial Transfer

Advanced Science, EarlyView.
PDGFA/PDGFRα signaling recruits CAFs to OSCC nests, and CAF‐OSCC contact drives tumor budding invasion. Mechanistically, heterotypic adhesion via E‐cadherin/integrin α2β1 activates YAP signaling in OSCC cells, inducing EMT. Concurrently, CAFs transfer mitochondria through TNTs, supplying ATP to fuel invasion.
Yufang Liu, Jiao Li, Juan Liu, Qi Dong, Haoyang Zhang, Yanjin Wang, Huibing Li, Ye Guan, Lei Cao, Manqing Zhang, Fangning Guo, Xue Liu, Zhen Yang, Mengmeng Lu, Hui Liu, Laiping Zhong, Tong Ji, Tingjiao Liu   +17 more
wiley   +1 more source

Somatic cell count of milk from different goat breeds

Acta Universitatis Sapientiae: Alimentaria, 2015
There is no standard limit value for somatic cell count (SCC) of raw goat milk in the EU despite that excellent hygienic quality milk is needed for the manufacture of fermented milk products or cheese varieties.
Csanádi J., Fenyvessy J., Bohata S.
doaj   +1 more source

Lymph Node Metastasis Pattern and Influencing Factors in Esophageal Squamous Cell Carcinoma

AGING MEDICINE, EarlyView.
Among 388 patients with esophageal squamous cell carcinoma who underwent curative resection, 144 (37.1%) developed lymph node metastasis. Upper thoracic tumors mainly involved upper mediastinal and upper right paratracheal nodes, whereas lower thoracic tumors more often involved paracardial and abdominal nodes.
Yuheng Wang, Qingqing Ding, Lei Xue, Jinhua Luo   +3 more
wiley   +1 more source

Cost‐Benefit Analysis of the European Union Carbon Border Adjustment Mechanism in Fertilizer Trade

Agribusiness, EarlyView.
ABSTRACT The carbon border adjustment mechanism (CBAM), launching 2026, will charge EU importers for embedded carbon emissions, aiming to reduce emissions but raising import costs. Shifts in demand following implementation may reduce carbon emissions, but importers will bear the cost of increased prices.
Natalie Crisci, Md Deluair Hossen, Andrew Muhammad, Seong‐Hoon Cho   +3 more
wiley   +1 more source

Role of HPV in anal squamous cell carcinoma: a narrative review with systematized search

Revista Médica de Minas Gerais
INTRODUCTION: The incidence and mortality of anal squamous cell carcinoma (SCC) has been increasing in recent decades. An association between anogenital infection by human papillomavirus (HPV) and the development of related neoplasms has been described.
Fernando Augusto Figueiredo Montandon, Eduardo Ângelo Braga, Iure Kalinine Ferraz de Souza, Claudia Martins Carneiro, Anderson Ribeiro Duarte, Sávio Lana Siqueira, Fernanda da Cruz Leão, Sarhan Sydney Saad   +7 more
doaj   +1 more source