Results 51 to 60 of about 190,501 (299)
Медицинская иммунология, 2014 Uterine cervical cancer is among the main items of modern oncology. Determination of SCCA levels in blood serum of women with locally disseminated forms of uterine cervical cancer has a great significance for estimation the extent of lesions, tumor ...
I. L. Baturina +5 more
doaj +1 more source
Deep Contrastive Learning for High‐Throughput Prediction of Drug Resistance Mutations from Sequences
Advanced Science, EarlyView.This study presents DeepMutDTA, a deep learning framework aimed at predicting mutation‐induced changes in protein‐drug interactions and prioritizing variants potentially linked to drug resistance. Trained on large‐scale data, it incorporates SimSiam‐MuTF, a label‐aware contrastive fine‐tuning strategy that encourages separation between WT and MT ...
Xiaowen Hu +7 more
wiley +1 more source
Behavior of RC Beams Under Two Points Load with Different Out-of-Plane Parts
Civil and Environmental EngineeringThis study focused on the out-of-plane beam behavior and the reduction caused by changes in the longitudinal axis and the out-of-plane span length in addition to the effect of adding torsion reinforcement.
Muhammed Nura Jasim, Al-Azzawi Adel A.
doaj +1 more source
Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV
Advanced Science, EarlyView.Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes +14 more
wiley +1 more source
Mandibular squamous cell carcinoma in a captive Siberian tiger (Panthera tigris altaica)
Brazilian Journal of Veterinary Pathology, 2018 Squamous cell carcinoma (SCC) is a common oral neoplasm in domestic cats, but there are only a few reports in wild felids. A captive 10-years-old, female Siberian tiger (Panthera tigris altaica), with history of chronic renal disease and serologically ...
Ayisa R. de Oliveira +9 more
doaj +1 more source
In vivo PET imaging of UM-SCC-22B xenografted mice by [18F]FP-Met-pep1.
, 2018 (A) Decay-corrected whole-body coronal microPET images of UM-SCC-22B tumor-bearing mice at 30, 60 and 120 min after injection of 3.7 MBq (100 μCi) of [18F]FP-Met-pep1. Arrows indicate tumor on right shoulder. (B) Quantification of [18F]FP-Met-pep1 uptake
Shaodong Cao (5374496) +5 more
core +1 more source
Advanced Science, EarlyView.Deep‐learning‐based signal enhancement is an effective way to recover high‐resolution details from a low‐resolution chromatin contact map. However, due to computational challenges, existing methods commonly divide up the contact map into small patches and create artificial discontinuities at patch boundaries.
Qinyao Li +6 more
wiley +1 more source
Somatic cell count of milk from different goat breeds
Acta Universitatis Sapientiae: Alimentaria, 2015 There is no standard limit value for somatic cell count (SCC) of raw goat milk in the EU despite that excellent hygienic quality milk is needed for the manufacture of fermented milk products or cheese varieties.
Csanádi J., Fenyvessy J., Bohata S.
doaj +1 more source
Advanced Science, EarlyView.PDGFA/PDGFRα signaling recruits CAFs to OSCC nests, and CAF‐OSCC contact drives tumor budding invasion. Mechanistically, heterotypic adhesion via E‐cadherin/integrin α2β1 activates YAP signaling in OSCC cells, inducing EMT. Concurrently, CAFs transfer mitochondria through TNTs, supplying ATP to fuel invasion.
Yufang Liu +17 more
wiley +1 more source
Role of HPV in anal squamous cell carcinoma: a narrative review with systematized search
Revista Médica de Minas GeraisINTRODUCTION: The incidence and mortality of anal squamous cell carcinoma (SCC) has been increasing in recent decades. An association between anogenital infection by human papillomavirus (HPV) and the development of related neoplasms has been described.
Fernando Augusto Figueiredo Montandon +7 more
doaj +1 more source