Results 91 to 100 of about 12,028 (205)

Non‐Membrane Active Peptide Resensitizes MRSA to β‐Lactam Antibiotics and Inhibits S. aureus Virulence

Advanced Science, Volume 12, Issue 15, April 17, 2025.
This work identifies a potent, non‐membrane active, and non‐toxic AMP termed GN1, which substantially resensitizes MRSA to multiple β‐lactam antibiotics at low concentrations. GN1 functions by suppressing MRSA‐associated resistance determinants, including penicillin‐binding protein 2a (PBP2a) and β‐lactamase.
Jingru Shi, Chen Chen, Pan Kong, Feiyu Yu, Qingyan Lv, Zhiqiang Wang, Yuan Liu   +6 more
wiley   +1 more source

Molecular characterization of resistance to Rifampicin in an emerging hospital-associated Methicillin-resistant Staphylococcus aureus clone ST228, Spain [PDF]

, 2010
Background: Methicillin-resistant S. aureus (MRSA) has been endemic in Hospital Universitari de Bellvitge, Barcelona, since 1990. During the 1990-95 period the Iberian clone (ST-247; SCCmec-I) was dominant. Isolates of clonal complex 5 (ST-125; SCCmec-IV)
Fe Tubau, Josefina Liñares, M Angeles Domínguez, Miquel Pujol, Rogelio Martín, Virginie Mick   +5 more
core   +1 more source

Complicated and deep bacterial skin and soft tissue infections

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 3, Page 357-375, March 2025.
Summary Complicated erysipelas, cellulitis, and necrotizing soft tissue infections belong to the spectrum of bacterial infections affecting the skin and underlying soft tissues. Their frequency as well as risk of recurrence and complicated disease course pose a significant health burden.
Christine Prodinger, Arno Lechner, Arno Hintersteininger, Jan Marco Kern, Matthias Meißnitzer, Damian Meyersburg, Johann W. Bauer, Martin Laimer   +7 more
wiley   +1 more source

CC8 MRSA Strains Harboring SCCmec Type IVc are Predominant in Colombian Hospitals

PLoS ONE, 2012
Contexte Des rapports récents soulignent l'incursion du SARM associé à la communauté dans les établissements de soins de santé. Cependant, la connaissance de ce phénomène reste limitée en Amérique latine. L'objectif de cette étude était d'évaluer l'épidémiologie moléculaire du SARM dans trois hôpitaux de soins tertiaires à Medellín, en Colombie ...
J. Natalia Jiménez, Ana M. Ocampo, Johanna M. Vanegas, Erika A. Rodríguez, José R. Mediavilla, Liang Chen, Carlos Muskus, Lázaro A. Vélez, Carlos Rojas, Andrea Restrepo, Sigifredo Ospina, Carlos Garcés, Liliana Franco, Pablo Bifani, Barry N. Kreiswirth, Margarita M. Correa   +15 more
openaire   +5 more sources

PFGE diversity within the methicillin-resistant Staphylococcus aureus clonal lineage ST398 [PDF]

, 2010
Background Livestock has recently been identified as a new reservoir of methicillin-resistant Staphylococcus aureus (MRSA). Most isolates belong to ST398 and are non-typeable with PFGE using SmaI, making it difficult to study transmission and outbreaks ...
Bosch, T., Neeling, A.J. de, Schouls, L.M., Zwaluw, K.W. van der, Kluijtmans, J.A.J.W., Grundmann, H., Huijsdens, X.W.   +6 more
core   +3 more sources

Komplizierte und tiefe bakterielle Haut‐ und Weichteilinfektionen

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 3, Page 357-376, March 2025.
Zusammenfassung Komplizierte Erysipele, Phlegmone und nekrotisierende Weichteilinfektionen sind bakterielle Haut‐ und Weichteilinfektionen (BHWI), die aufgrund ihrer Häufigkeit, der Neigung zu Rezidiven und dem Auftreten komplizierter Verläufe ein bedeutendes Gesundheitsproblem darstellen.
Christine Prodinger, Arno Lechner, Arno Hintersteininger, Jan Marco Kern, Matthias Meißnitzer, Damian Meyersburg, Johann W. Bauer, Martin Laimer   +7 more
wiley   +1 more source

Novel staphylococcal cassette chromosome mec (SCCmec) type XIV (5A) and a truncated SCCmec element in SCC composite islands carrying speG in ST5 MRSA in Japan

Journal of Antimicrobial Chemotherapy, 2019
Abstract Background Staphylococcal cassette chromosome mec (SCCmec) elements are highly diverse and have been classified into 13 types. The arginine catabolic mobile element (ACME) is an SCC-like element harbouring an arginine deiminase pathway gene cluster (ACME-arc).
Noriko, Urushibara, Meiji Soe, Aung, Mitsuyo, Kawaguchiya, Nobumichi, Kobayashi   +3 more
openaire   +2 more sources

Staphylococcal Chromosomal Cassette Type in Clinical Strains of Methicillin-Resistant Staphylococcus aureus

Kasmera, 2014
Methicillin-resistant Staphylococcus aureus (MRSA) presents a protein that binds to penicillin, the PBP2a, encoded by the gene mecA, located in a mobile genetic element called the staphylococcal chromosomal cassette (SCCmec).
Maribel J. Castellano González, María E Cavazza Porro, Armindo J Perozo Mena   +2 more
doaj  

Staphylococcal Cassette Chromosome mec, Evolution and Genetic Lines of Methicillin Resistant Staphylococcus aureus

Антибиотики и Химиотерапия, 2020
Methicillin resistant Staphylococcus aureus (MRSA) is the main pathogen of hospital- and community-associated infections. Methicillin resistance is due to mecA gene located in a mobile complex element, staphylococcal cassette chromosome mec (SCCmec). The
V. V. Gostev, S. V. Sidorenko
doaj  

Molecular characterization of methicillin-resistant Staphylococcus aureus isolated from a Brazilian university hospital

Brazilian Journal of Infectious Diseases, 2014
The aim of this study was to perform SCCmec typing in Staphylococcus aureus isolates and to characterize the clonal profile of these isolates. Forty-six mecA gene-positive strains isolated between 2002 and 2006 were submitted to antimicrobial resistance ...
André Martins, Danilo Flávio Moraes Riboli, Valéria Cataneli Pereira, Maria de Lourdes Ribeiro de Souza da Cunha   +3 more
doaj   +1 more source