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Methicillin resistant Staphylococcus aureus (MRSA) is the main pathogen of hospital- and community-associated infections. Methicillin resistance is due to mecA gene located in a mobile complex element, staphylococcal cassette chromosome mec (SCCmec). The
V. V. Gostev, S. V. Sidorenko
doaj
The aim of this study was to perform SCCmec typing in Staphylococcus aureus isolates and to characterize the clonal profile of these isolates. Forty-six mecA gene-positive strains isolated between 2002 and 2006 were submitted to antimicrobial resistance ...
André Martins +3 more
doaj +1 more source
Complete genome sequence of methicillin-sensitive Staphylococcus aureus containing a heterogeneic staphylococcal cassette chromosome element [PDF]
Staphylococcus aureus is a common human bacterium that sometimes becomes pathogenic, causing serious infections. A key feature of S. aureus is its ability to acquire resistance to antibiotics.
A Bairoch +42 more
core +1 more source
The bacterial cell membrane and cell wall are the primary targets of baicalin. Baicalin increases the permeability of bacterial membranes, allowing oxacillin sodium to easily penetrate the cells and effectively exert its antimicrobial activity. Methicillin‐resistant Staphylococcus aureus (MRSA) poses a challenge for clinical treatment and combining ...
Xin Meng +7 more
wiley +1 more source
Resistance of methicillin resistant Staphylococcus aureus (MRSA) were based mainly on insertion of mobile genetic elements namely Staphylococcal cassette chromosome mec (SCCmec) in the chromosome of Staphylococcus aureus.
Sunarjati Sudigdoadi
doaj
Typing of methicillin-resistant Staphylococcus aureus (MRSA) is important in infection control and surveillance. The current nomenclature of MRSA includes the genetic background of the S.
Hülya Kaya +9 more
doaj +1 more source
Performance of a Machine Learning-Based Methicillin Resistance of Staphylococcus aureus Identification System Using MALDI-TOF MS and Comparison of the Accuracy according to SCCmec Types [PDF]
Kibum Jeon +5 more
openalex +1 more source
This work identifies a potent, non‐membrane active, and non‐toxic AMP termed GN1, which substantially resensitizes MRSA to multiple β‐lactam antibiotics at low concentrations. GN1 functions by suppressing MRSA‐associated resistance determinants, including penicillin‐binding protein 2a (PBP2a) and β‐lactamase.
Jingru Shi +6 more
wiley +1 more source
High Prevalence and Resistance Patterns of Community-Associated Methicillin-Resistant Staphylococcus aureus in the Pomoravlje Region, Serbia [PDF]
With a view to estimating the prevalence and resistance patterns of CA-MRSA in one region of Serbia, we performed an analysis of MRSA isolates from healthy people and hospitalised patients. The detection of CA-MRSA was carried out by SCCmec typing.
Cirkovic, Ivana +3 more
core +1 more source
Complicated and deep bacterial skin and soft tissue infections
Summary Complicated erysipelas, cellulitis, and necrotizing soft tissue infections belong to the spectrum of bacterial infections affecting the skin and underlying soft tissues. Their frequency as well as risk of recurrence and complicated disease course pose a significant health burden.
Christine Prodinger +7 more
wiley +1 more source

