Results 51 to 60 of about 6,009 (171)

A Hypervirulent Community‐Associated Methicillin‐Resistant Staphylococcus aureus Sequence Type 59 Strain Shows Enhanced Cytotoxicity and Accessory Gene Regulator Activation Compared With Strain USA300

International Journal of Microbiology, Volume 2026, Issue 1, 2026.
Background Different clonal groups of methicillin‐resistant Staphylococcus aureus (MRSA), particularly community‐acquired MRSA (CA‐MRSA), have caused widespread outbreaks and transmission in various regions. Methods We used the North American CA‐MRSA epidemic strain USA300, the Asian CA‐MRSA epidemic strain YNSA7, and ATCC43300 as research subjects ...
Feng Liao, Na Dai, Ning Zou, Yu Shi, Wenpeng Gu, Bing Yuan, Ziqing Li   +6 more
wiley   +1 more source

Genetic Diversity of Methicillin‐Resistant Staphylococcus aureus Isolates From Two Tertiary Care Hospitals in Sulaymaniyah, Iraq, Characterized by spa Typing, Coagulase VNTR Sequencing, and REP‐PCR

International Journal of Microbiology, Volume 2026, Issue 1, 2026.
Background Methicillin‐resistant Staphylococcus aureus remains a major cause of health care‐associated infection in high‐risk units such as burn and cancer wards. In settings where advanced genotyping schemes are not routinely available, combining complementary molecular typing methods can improve characterization of genetic diversity for surveillance ...
Alan O. Shwan, Sahand K. Arif, Heide Schatten   +2 more
wiley   +1 more source

SCCmec transformation requires living donor cells in mixed biofilms

Biofilm
Methicillin-resistant Staphylococcus aureus (MRSA) is an important human pathogen that has emerged through the horizontal acquisition of the staphylococcal cassette chromosome mec (SCCmec). Previously, we showed that SCCmec from heat-killed donors can be transferred via natural transformation in biofilms at frequencies of 10-8-10-7.
Mais Maree, Yuri Ushijima, Pedro B. Fernandes, Masato Higashide, Kazuya Morikawa   +4 more
openaire   +4 more sources

Emergence of Livestock‐Associated Methicillin‐Resistant Staphylococcus aureus ST398 in Wild Birds, Brazil

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
In a protected forest fragment in southern Brazil, 197 wild birds were sampled, with 12.2% carrying Staphylococcus aureus. Two MRSA ST398 strains, the first reported in Brazilian wild birds, were identified. Genomic analysis revealed resistance and virulence genes, linking these strains to pigs and underscoring the critical need for resistance ...
Mateus Rocha Ribas, Felipe Vásquez‐Ponce, Rodrigo Cardoso, Dany Mesa, Gustavo Rocha, Victor Felipe Wolleck, Juliana Lemos Dal Pizzol, Izadora Borgmann Frizzo de Assunção, Vinicius Pais e Oliveira, Gabriel Salvador, Amanda Tfardoski Rodrigues, Gregory Batista Melocco, Fernanda Esposito, Johana Becerra, Nilton Lincopan, Fabienne Antunes Ferreira, Thaís Cristine Marques Sincero, Jussara Kasuko Palmeiro, Sheila Rezler Wosiacki, Silvia Cristina Osaki   +19 more
wiley   +1 more source

Community-acquired methicillin-resistant Staphylococcus aureus from ST1 lineage harboring a new SCCmec IV subtype (SCCmec IVm) containing the tetK gene.

Infection and drug resistance, 2018
A pivotal event in the evolutionary path of methicillin-resistant Staphylococcus aureus (MRSA) is the acquisition of the staphylococcal cassette chromosome mec (SCCmec) element carrying the mecA gene, the determinant of methicillin resistance. Community-acquired (CA) MRSA is commonly associated with skin/soft tissue infections, and doxycycline is one ...
Côrtes,Marina F., Botelho,Ana M. N., Almeida,Luiz G. P., Souza,Rangel C., Cunha,Oberdan de Lima, Nicolás,Marisa F., Vasconcelos,Ana T. R., Figueiredo,Agnes M. S.   +7 more
openaire   +5 more sources

Diversity of SCCmec Elements in Staphylococcus aureus as Observed in South-Eastern Germany

PLOS ONE, 2016
SCCmec elements are very important mobile genetic elements in Staphylococci that carry beta-lactam resistance genes mecA/mecC, recombinase genes and a variety of accessory genes. Twelve main types and a couple of variants have yet been described. In addition, there are also other SCC elements harbouring other markers.
Stefan Monecke, Lutz Jatzwauk, Elke Müller, Hedda Nitschke, Katharina Pfohl, Peter Slickers, Annett Reissig, Antje Ruppelt-Lorz, Ralf Ehricht   +8 more
openaire   +4 more sources

The Host R‐M Systems Change the Host Range of Staphylococcus Phage EBHT

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
The study shows how Staphylococcal restriction–modification (R‐M) systems methylate the phage genomic DNA and change the phage host range. The host R‐M systems should be considered when selecting phage manufacturing hosts, as the manufacturing host with a higher yield can result in a narrower phage host range.
Henni Tuomala, Julia Holtel, Melina Markkanen, Sheetal Patpatia, Katariina Kaansalo, Clara Rolland, Oliver W. Bayfield, Kira Ranta, Mikael Skurnik, Johannes Wittmann, Saija Kiljunen   +10 more
wiley   +1 more source

Tipo de cassette cromosómico estafilocócico en cepas clínicas de Staphylococcus aureus resistentes a meticilina

Kasmera, 2014
: Methicillin-resistant Staphylococcus aureus (MRSA) presents a protein that binds to penicillin, the PBP2a, encoded by the gene mecA, located in a mobile genetic element called the staphylococcal chromosomal cassette (SCCmec).
Castellano González Maribel J, Cavazza Porro María E, Perozo Mena Armindo J   +2 more
doaj  

Antibiotic Resistance: A Genetic and Physiological Perspective

MedComm, Volume 6, Issue 11, November 2025.
The development of resistance to antimicrobials and their historical progression are depicted in this graphic. It draws attention to important biochemical, physiological, and genetic factors that contribute to AMR, such as the transmission of genes, the development of biofilms, and the inactivation of antibiotics.
Rania G. Elbaiomy, Ahmed H. El‐Sappah, Rong Guo, Xiaoling Luo, Shiyuan Deng, Meifang Du, Xiaohong Jian, Mohammed Bakeer, Zaixin Li, Zhi Zhang   +9 more
wiley   +1 more source

Quorum Sensing Inhibits Type III‐A CRISPR‐Cas System Activity Through Repressing Positive Regulators SarA and ArcR in Staphylococcus Aureus

Advanced Science, Volume 12, Issue 36, September 25, 2025.
This study proposes a novel model illustrating how quorum sensing (QS) regulates the type III‐A CRISPR‐Cas system in Staphylococcus aureus. The QS regulator AgrA suppresses CRISPR‐Cas activity by downregulating the transcriptional regulators SarA and ArcR.
Yang Li, Yuanyue Tang, Xiaofei Li, Nina Molin Høyland‐Kroghsbo, Hanne Ingmer, Xinan Jiao, Qiuchun Li   +6 more
wiley   +1 more source