Results 71 to 80 of about 8,410 (203)

Novel staphylococcal cassette chromosome mec (SCCmec) type XIV (5A) and a truncated SCCmec element in SCC composite islands carrying speG in ST5 MRSA in Japan

open access: yesJournal of Antimicrobial Chemotherapy, 2019
Abstract Background Staphylococcal cassette chromosome mec (SCCmec) elements are highly diverse and have been classified into 13 types. The arginine catabolic mobile element (ACME) is an SCC-like element harbouring an arginine deiminase pathway gene cluster (ACME-arc).
Noriko, Urushibara   +3 more
openaire   +2 more sources

Antibiotic Resistance: A Genetic and Physiological Perspective

open access: yesMedComm, Volume 6, Issue 11, November 2025.
The development of resistance to antimicrobials and their historical progression are depicted in this graphic. It draws attention to important biochemical, physiological, and genetic factors that contribute to AMR, such as the transmission of genes, the development of biofilms, and the inactivation of antibiotics.
Rania G. Elbaiomy   +9 more
wiley   +1 more source

Quorum Sensing Inhibits Type III‐A CRISPR‐Cas System Activity Through Repressing Positive Regulators SarA and ArcR in Staphylococcus Aureus

open access: yesAdvanced Science, Volume 12, Issue 36, September 25, 2025.
This study proposes a novel model illustrating how quorum sensing (QS) regulates the type III‐A CRISPR‐Cas system in Staphylococcus aureus. The QS regulator AgrA suppresses CRISPR‐Cas activity by downregulating the transcriptional regulators SarA and ArcR.
Yang Li   +6 more
wiley   +1 more source

Molecular characterization of methicillin-resistant Staphylococcus aureus isolated from a Brazilian university hospital

open access: yesBrazilian Journal of Infectious Diseases, 2014
The aim of this study was to perform SCCmec typing in Staphylococcus aureus isolates and to characterize the clonal profile of these isolates. Forty-six mecA gene-positive strains isolated between 2002 and 2006 were submitted to antimicrobial resistance ...
André Martins   +3 more
doaj   +1 more source

Staphylococcal Cassette Chromosome mec (SCCmec) Classification and Typing Methods: an Overview

open access: yesPolish Journal of Microbiology, 2011
Meticillin-resistant Staphylococcus aureus (MRSA) is one of the main causes of hospital-acquired infections, but since late 1990s also the community-acquired. For better understanding of the S.aureus epidemiology there is an urgent need for creation of new typing method for SCCmec element.
Turlej, Agata   +2 more
openaire   +2 more sources

Staphylococcus aureus COL: An Atypical Model Strain of MRSA That Exhibits Slow Growth and Antibiotic Tolerance due to a Mutation in PRPP Synthetase

open access: yesMolecular Microbiology, Volume 124, Issue 3, Page 189-203, September 2025.
COL is an unusual “model” strain of Staphylococcus aureus that exhibits slow growth and multidrug antibiotic tolerance. This phenotype is primarily due to a mutation in Prs, which synthesizes the core metabolite phosphoribosyl pyrophosphate (PRPP). Introduction of the COL Prs allele into the antibiotic‐susceptible strain Newman confers tolerance, while
Claire E. Stevens   +5 more
wiley   +1 more source

SCCmecFinder, a Web-Based Tool for Typing of Staphylococcal Cassette Chromosome mec in Staphylococcus aureus Using Whole-Genome Sequence Data

open access: yesmSphere, 2018
Typing of methicillin-resistant Staphylococcus aureus (MRSA) is important in infection control and surveillance. The current nomenclature of MRSA includes the genetic background of the S.
Hülya Kaya   +9 more
doaj   +1 more source

Association between SCCmec types and antimicrobial resistance in clinical MRSA isolates

open access: yes, 2022
Background: Methicillin resistant Staphylococcus aureus (MRSA) is the causative agent of serious infections. MRSA isolates carry mecA gene which confers resistance to all β-lactams, markedly limiting the therapeutic options ...
Aboulela, Aliaa   +3 more
core   +1 more source

Antibiotic Resistance, Biofilm Formation, and Molecular Epidemiology of Foodborne Staphylococcus aureus Isolated in Northwest Hubei Province, China

open access: yesFood Science &Nutrition, Volume 13, Issue 8, August 2025.
This study reveals a high prevalence of foodborne S. aureus in northwest Hubei Province, with MRSA strains displaying significantly elevated antibiotic resistance and biofilm‐forming capacities compared to MSSA strains. The high carriage rates of enterotoxin genes across isolates underscore the potential of these strains to contribute to foodborne ...
Yitong Tang   +8 more
wiley   +1 more source

Staphylococcal Chromosomal Cassette Type in Clinical Strains of Methicillin-Resistant Staphylococcus aureus

open access: yesKasmera, 2014
Methicillin-resistant Staphylococcus aureus (MRSA) presents a protein that binds to penicillin, the PBP2a, encoded by the gene mecA, located in a mobile genetic element called the staphylococcal chromosomal cassette (SCCmec).
Maribel J. Castellano González   +2 more
doaj  

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