Results 61 to 70 of about 6,028 (174)
Background Bloodstream infections caused by Staphylococcus aureus (S. aureus) and its methicillin‐resistant S. aureus (MRSA) represent a major clinical challenge, contributing to prolonged illness, increased healthcare costs, and high mortality worldwide. In low‐resource settings, these infections are further aggravated by overcrowding, poor sanitation,
Jeremiah Ogeto +5 more
wiley +1 more source
To trace the linkage between Japanese healthcare-associated methicillin-resistant Staphylococcus aureus (HA-MRSA) strains in the early 1980s and the 2000s onward, we performed molecular characterizations using mainly whole-genome sequencing.
Hui Zuo +4 more
doaj +1 more source
Background Necrotizing pneumonia is a severe and potentially fatal complication of community‐acquired pneumonia, often associated with toxin‐producing or drug‐resistant pathogens. Rapid and accurate identification of these pathogens is crucial for timely intervention. Polymerase chain reaction (PCR)–based diagnostic tools, such as the BioFire FilmArray
Po-Kai Chan, Chun-Han Wu, Priya Gusain
wiley +1 more source
Methicillin-resistant Staphylococcus lugdunensis carrying SCCmec type V misidentified as MRSA [PDF]
Staphylococcus lugdunensis is a rare cause of severe infections and clinical manifestations are similar to those related to S. aureus infection. We describe a hospital-acquired bacteremia due to methicillin-resistant Staphylococcus lugdunensis, misidentified as methicillin-resistant S. aureus. The oxacillin MIC was 16 µg/mL and the mecA gene and SCCmec
Eliezer Menezes Pereira +3 more
openaire +4 more sources
Methicillin‐resistant Staphylococcus aureus (MRSA) is a major cause of multidrug‐resistant and biofilm‐associated infections, particularly on indwelling medical devices, where conventional antibiotics often exhibit limited efficacy. In this study, we isolated and characterized a novel lytic bacteriophage, SA_SGEB_01, targeting MRSA from hospital ...
Raphael Kabir Niloy +11 more
wiley +1 more source
A pivotal event in the evolutionary path of methicillin-resistant Staphylococcus aureus (MRSA) is the acquisition of the staphylococcal cassette chromosome mec (SCCmec) element carrying the mecA gene, the determinant of methicillin resistance. Community-acquired (CA) MRSA is commonly associated with skin/soft tissue infections, and doxycycline is one ...
Côrtes,Marina F. +7 more
openaire +5 more sources
: Methicillin-resistant Staphylococcus aureus (MRSA) presents a protein that binds to penicillin, the PBP2a, encoded by the gene mecA, located in a mobile genetic element called the staphylococcal chromosomal cassette (SCCmec).
Castellano González Maribel J +2 more
doaj
Diversity of SCCmec Elements in Staphylococcus aureus as Observed in South-Eastern Germany
SCCmec elements are very important mobile genetic elements in Staphylococci that carry beta-lactam resistance genes mecA/mecC, recombinase genes and a variety of accessory genes. Twelve main types and a couple of variants have yet been described. In addition, there are also other SCC elements harbouring other markers.
Stefan Monecke +8 more
openaire +4 more sources
Background Different clonal groups of methicillin‐resistant Staphylococcus aureus (MRSA), particularly community‐acquired MRSA (CA‐MRSA), have caused widespread outbreaks and transmission in various regions. Methods We used the North American CA‐MRSA epidemic strain USA300, the Asian CA‐MRSA epidemic strain YNSA7, and ATCC43300 as research subjects ...
Feng Liao +6 more
wiley +1 more source
Background Methicillin‐resistant Staphylococcus aureus remains a major cause of health care‐associated infection in high‐risk units such as burn and cancer wards. In settings where advanced genotyping schemes are not routinely available, combining complementary molecular typing methods can improve characterization of genetic diversity for surveillance ...
Alan O. Shwan +2 more
wiley +1 more source

