Results 81 to 90 of about 6,028 (174)

Quorum Sensing Inhibits Type III‐A CRISPR‐Cas System Activity Through Repressing Positive Regulators SarA and ArcR in Staphylococcus Aureus

Advanced Science, Volume 12, Issue 36, September 25, 2025.
This study proposes a novel model illustrating how quorum sensing (QS) regulates the type III‐A CRISPR‐Cas system in Staphylococcus aureus. The QS regulator AgrA suppresses CRISPR‐Cas activity by downregulating the transcriptional regulators SarA and ArcR.
Yang Li, Yuanyue Tang, Xiaofei Li, Nina Molin Høyland‐Kroghsbo, Hanne Ingmer, Xinan Jiao, Qiuchun Li   +6 more
wiley   +1 more source

Staphylococcal Cassette Chromosome mec, Evolution and Genetic Lines of Methicillin Resistant Staphylococcus aureus

Антибиотики и Химиотерапия, 2020
Methicillin resistant Staphylococcus aureus (MRSA) is the main pathogen of hospital- and community-associated infections. Methicillin resistance is due to mecA gene located in a mobile complex element, staphylococcal cassette chromosome mec (SCCmec). The
V. V. Gostev, S. V. Sidorenko
doaj  

Staphylococcus aureus COL: An Atypical Model Strain of MRSA That Exhibits Slow Growth and Antibiotic Tolerance due to a Mutation in PRPP Synthetase

Molecular Microbiology, Volume 124, Issue 3, Page 189-203, September 2025.
COL is an unusual “model” strain of Staphylococcus aureus that exhibits slow growth and multidrug antibiotic tolerance. This phenotype is primarily due to a mutation in Prs, which synthesizes the core metabolite phosphoribosyl pyrophosphate (PRPP). Introduction of the COL Prs allele into the antibiotic‐susceptible strain Newman confers tolerance, while
Claire E. Stevens, Ashley T. Deventer, Paul R. Johnston, Phillip T. Lowe, Alisdair B. Boraston, Joanne K. Hobbs   +5 more
wiley   +1 more source

Staphylococcus aureus resistente a meticilina causante de infecciones comunitarias y de infecciones asociadas a la atención en salud en pacientes pediátricos del Hospital Universitario de Santander

Biomédica: revista del Instituto Nacional de Salud, 2014
Introducción. Staphylococcus aureus resistente a la meticilina (SARM) es un agente frecuente de infección en la población pediátrica. Aunque inicialmente las cepas de SARM estaban restringidas a los hospitales, se han reportado a nivel mundial brotes de ...
Mayra Alejandra Machuca, Clara Isabel González, Luis Miguel Sosa   +2 more
doaj   +1 more source

Antibiotic Resistance, Biofilm Formation, and Molecular Epidemiology of Foodborne Staphylococcus aureus Isolated in Northwest Hubei Province, China

Food Science &Nutrition, Volume 13, Issue 8, August 2025.
This study reveals a high prevalence of foodborne S. aureus in northwest Hubei Province, with MRSA strains displaying significantly elevated antibiotic resistance and biofilm‐forming capacities compared to MSSA strains. The high carriage rates of enterotoxin genes across isolates underscore the potential of these strains to contribute to foodborne ...
Yitong Tang, Yanyan Li, Na Xiao, Lu Wang, Shichao Li, JiuMing Zou, Yanmin Yu, Jinhui Shao, Ming Jiang   +8 more
wiley   +1 more source

The prevalence, antibiotic resistance and mecA characterization of coagulase negative staphylococci recovered from non-healthcare settings in London, UK

Antimicrobial Resistance and Infection Control, 2018
Background Coagulase negative staphylococci (CoNS) are important reservoirs of antibiotic resistance genes and associated mobile genetic elements and are believed to contribute to the emergence of successful methicillin resistant Staphylococcus aureus ...
Zhen Xu, Haroun N. Shah, Raju Misra, Jiazhen Chen, Wenhong Zhang, Yuting Liu, Ronald R. Cutler, Hermine V. Mkrtchyan   +7 more
doaj   +1 more source

SCCmec transformation requires living donor cells in mixed biofilms

Biofilm
Methicillin-resistant Staphylococcus aureus (MRSA) is an important human pathogen that has emerged through the horizontal acquisition of the staphylococcal cassette chromosome mec (SCCmec). Previously, we showed that SCCmec from heat-killed donors can be transferred via natural transformation in biofilms at frequencies of 10-8-10-7.
Mais Maree, Yuri Ushijima, Pedro B. Fernandes, Masato Higashide, Kazuya Morikawa   +4 more
openaire   +3 more sources

SCCmec Genotypes of Methicillin-Resistant Staphylococcus aureus in Nasal Carriage of Multiple Sclerosis Patients in Iran

Iranian Journal of Public Health, 2019
Background: Asymptomatic nasal colonization of Methicillin-Resistant Staphylococcus aureus is common in Multiple Sclerosis patients. SCCmec types I to III are mainly attributed to HA-MRSA strains whereas SCCmec types IV and V have commonly been reported ...
Yasaman JAMSHIDI, Mohammad Reza POURMAND, Zahra PAKBAZ, Amirhossein POURMAND, Abbas RAHIMI FOROUSHANI, Mohammad Ali SAHRAIAN   +5 more
doaj   +1 more source

Staphylococcal Cassette Chromosome mec (SCCmec) in coagulase negative staphylococci

Medicina Universitaria, 2015
AbstractCoagulase-negative staphylococci (CoNS) are among the main causative agents of bacteremia. Staphylococcus epidermidis and Staphylococcus haemolyticus are the CoNS species most frequently isolated. These species are often associated with infections in immunocompromised patients who have a medical device implant.
Martínez Meléndez, Julio Adrián, Morfín Otero, Rayo, Villarreal Treviño, Licet, González González, Gloria María, Llaca Díaz, Jorge Martín, Rodríguez Noriega, Eduardo, Camacho Ortiz, Adrián, Garza González, Elvira   +7 more
openaire   +1 more source

An unexpected location of the arginine catabolic mobile element (ACME) in a USA300-related MRSA strain.

PLoS ONE, 2011
In methicillin resistant Staphylococcus aureus (MRSA), the arginine catabolic mobile element (ACME) was initially described in USA300 (t008-ST8) where it is located downstream of the staphylococcal cassette chromosome mec (SCCmec).
Mette Damkjær Bartels, Lars Hestbjerg Hansen, Kit Boye, Søren J Sørensen, Henrik Westh   +4 more
doaj   +1 more source