Results 71 to 80 of about 9,202 (212)
A large intracellular drug‐repurposing screen identifies a potent synergy between 5‐fluoro‐2′‐deoxycytidine and rifapentine, acting through dual host–pathogen targeting to reduce Staphylococcus aureus burdens across strains, cell types, and infection models (created with BioRender).
Blanca Lorente‐Torres +13 more
wiley +1 more source
ABSTRACT Introduction The emergence of methicillin‐resistant Staphylococcus species (MRS) poses a growing threat to both human and veterinary health. Methods We performed a comparative genomic characterisation of 49 methicillin‐resistant Staphylococcus isolates collected from humans, dogs, and cats in a veterinary hospital from Central Chile.
Daniel Garrido +7 more
wiley +1 more source
Strategies of adaptation of Staphylococcus epidermidis to hospital and community: amplification and diversification of SCCmec [PDF]
Staphylococcus epidermidis is a harmless commensal, but it can become a human pathogen, mainly in the hospital environment. In order to clarify strategies used by these bacteria to adapt to the hospital environment, we compared the population structure and staphylococcal cassette chromosome mec (SCCmec) content of S.
Rolo, J., de Lencastre, H., Miragaia, M.
openaire +2 more sources
: Methicillin-resistant Staphylococcus aureus (MRSA) presents a protein that binds to penicillin, the PBP2a, encoded by the gene mecA, located in a mobile genetic element called the staphylococcal chromosomal cassette (SCCmec).
Castellano González Maribel J +2 more
doaj
Abstract This report presents the main findings of the 2023–2024 harmonised antimicrobial resistance (AMR) monitoring in Salmonella spp., Campylobacter jejuni and Campylobacter coli from humans, food‐producing animals (broilers, laying hens, fattening turkeys, fattening pigs and bovines under 1 year of age), and derived meat.
European Food Safety Authority (EFSA) +1 more
wiley +1 more source
Background Bloodstream infections caused by Staphylococcus aureus (S. aureus) and its methicillin‐resistant S. aureus (MRSA) represent a major clinical challenge, contributing to prolonged illness, increased healthcare costs, and high mortality worldwide. In low‐resource settings, these infections are further aggravated by overcrowding, poor sanitation,
Jeremiah Ogeto +5 more
wiley +1 more source
Methicillin-resistant Staphylococcus lugdunensis carrying SCCmec type V misidentified as MRSA [PDF]
Staphylococcus lugdunensis is a rare cause of severe infections and clinical manifestations are similar to those related to S. aureus infection. We describe a hospital-acquired bacteremia due to methicillin-resistant Staphylococcus lugdunensis, misidentified as methicillin-resistant S. aureus. The oxacillin MIC was 16 µg/mL and the mecA gene and SCCmec
Eliezer Menezes Pereira +3 more
openaire +4 more sources
A pivotal event in the evolutionary path of methicillin-resistant Staphylococcus aureus (MRSA) is the acquisition of the staphylococcal cassette chromosome mec (SCCmec) element carrying the mecA gene, the determinant of methicillin resistance. Community-acquired (CA) MRSA is commonly associated with skin/soft tissue infections, and doxycycline is one ...
Côrtes,Marina F. +7 more
openaire +5 more sources
The aim of this study was to perform SCCmec typing in Staphylococcus aureus isolates and to characterize the clonal profile of these isolates. Forty-six mecA gene-positive strains isolated between 2002 and 2006 were submitted to antimicrobial resistance ...
André Martins +3 more
doaj +1 more source
Background Necrotizing pneumonia is a severe and potentially fatal complication of community‐acquired pneumonia, often associated with toxin‐producing or drug‐resistant pathogens. Rapid and accurate identification of these pathogens is crucial for timely intervention. Polymerase chain reaction (PCR)–based diagnostic tools, such as the BioFire FilmArray
Po-Kai Chan, Chun-Han Wu, Priya Gusain
wiley +1 more source

