Results 31 to 40 of about 12,028 (205)

Evidence for the evolutionary steps leading to mecA-mediated ß-lactam resistance in staphylococci [PDF]

, 2017
The epidemiologically most important mechanism of antibiotic resistance in Staphylococcus aureus is associated with mecA–an acquired gene encoding an extra penicillin-binding protein (PBP2a) with low affinity to virtually all β-lactams.
Bouchami, O, Bowden, R, Boye Nielsen, J, Damborg, P, de Lencastre, H, Guardabassi, L, Hughes, D, Miragaia, M, Perreten, V, Rolo, J, Sobral, R, Tomasz, A, Westh, H, Worning, P   +13 more
core   +6 more sources

Methicillin-resistant Staphylococcus lugdunensis carrying SCCmec type V misidentified as MRSA [PDF]

The Brazilian Journal of Infectious Diseases, 2011
Staphylococcus lugdunensis is a rare cause of severe infections and clinical manifestations are similar to those related to S. aureus infection. We describe a hospital-acquired bacteremia due to methicillin-resistant Staphylococcus lugdunensis, misidentified as methicillin-resistant S. aureus. The oxacillin MIC was 16 µg/mL and the mecA gene and SCCmec
Eliezer Menezes Pereira, Ricardo Pinto Schuenck, Simone Aranha Nouér, Kátia Regina Netto dos Santos   +3 more
openaire   +7 more sources

Novel rearrangements in the staphylococcal cassette chromosome mec type V elements of Indian ST772 and ST672 methicillin resistant Staphylococcus aureus strains. [PDF]

PLoS ONE, 2014
Staphylococcus aureus is a commensal gram positive bacteria which causes severe and non severe infections in humans and livestock. In India, ST772 is a dominant and ST672 is an emerging clone of Staphylococcus aureus.
Jayanth Balakuntla, Sushma Prabhakara, Gayathri Arakere   +2 more
doaj   +1 more source

Prevalence of qacA/B genes and mupirocin resistance among methicillin-resistant Staphylococcus aureus (MRSA) isolates in the setting of chlorhexidine bathing without mupirocin [PDF]

, 2016
OBJECTIVE: We aimed to determine the frequency of qacA/B chlorhexidine tolerance genes and high-level mupirocin resistance among MRSA isolates before and after the introduction of a chlorhexidine (CHG) daily bathing intervention in a surgical intensive ...
Bommarito, Kerry M, Burnham, Carey-Ann D, Kennedy, Colleen R, Mazuski, John E, Munigala, Satish, Prager, Martin, Wallace, Meghan A, Warren, David K   +7 more
core   +2 more sources

A novel DNA primase-helicase pair encoded by SCCmec elements

eLife, 2020
Mobile genetic elements (MGEs) are a rich source of new enzymes, and conversely, understanding the activities of MGE-encoded proteins can elucidate MGE function. Here, we biochemically characterize three proteins encoded by a conserved operon carried by the Staphylococcal Cassette Chromosome (SCC mec
Aleksandra Bebel, Melissa A Walsh, Ignacio Mir-Sanchis, Phoebe A Rice   +3 more
openaire   +5 more sources

Identification and characteristics of drug resistance and genotypes of methicillin-resistant Staphylococcus aureus isolated from intensive care units at obstetrics & gynaecology departments: a retrospective analysis

Clinical and Experimental Obstetrics & Gynecology, 2022
Background: The aim of this study was to investigate the prevalence and characteristics of SCCmec genotypes and drug resistance of methicillin-resistant Staphylococcus aureus (MRSA) isolated from intensive care units (ICU) at obstetrics & gynaecology ...
Zhonghua Huo, Binxian Li, Xue Meng, Peiyao Li, Mingcheng Li   +4 more
doaj   +1 more source

Genomic insights into the rapid emergence and evolution of MDR in Staphylococcus pseudintermedius. [PDF]

, 2014
OBJECTIVES: MDR methicillin-resistant Staphylococcus pseudintermedius (MRSP) strains have emerged rapidly as major canine pathogens and present serious treatment issues and concerns to public health due to their, albeit low, zoonotic potential. A further
A. J. McCarthy, A. Loeffler, A. Waller, B. Leggett, Bannoehr, Besier, Black, Bond, Croucher, D. H. Lloyd, Darling, De Lucia, E. M. Harrison, Feil, Feng, Geoghegan, Gortel, J. A. Lindsay, K. Stanczak-Mrozek, Kadlec, Koser, Loeffler, Loeffler, M. A. Holmes, Magiorakos, Noguchi, Prescott, Quail, Roberts, Ruscher, Rutherford, Soedarmanto   +31 more
core   +3 more sources

Detection of sasX Gene and Distribution of SCCmec Types in Invasive and Non-invasive Coagulase-negative Staphylococci

Balkan Medical Journal, 2020
Background: Coagulase-negative staphylococci, which belong to the normal microbiota of the skin and mucous membranes, are opportunistic pathogens. sasX, a newly described protein, is thought to play an important role in nasal colonization and methicillin-
Alper Tekeli, Duygu Nilüfer Öcal, İştar Dolapçı   +2 more
doaj   +1 more source

Methicillin-resistant Staphylococcus aureus (MRSA) ST398 associated with clinical and subclinical mastitis in Belgian cows [PDF]

, 2010
Methicillin-resistant Staphylococcus aureus (MRSA) is infrequently reported in mastitis. Yet, as in many other countries, the prevalence of methicillin resistance among S. aureus from mastitis is currently unknown in Belgium.
Adriaensen, Connie, Butaye, Patrick, Cerpentier, Tineke, Hermans, Katleen, Vanderhaeghen, Wannes, Vicca, Jo   +5 more
core   +1 more source

Detecting the frequency of aminoglycoside modifying enzyme encoding genes among clinical isolates of methicillin-resistant Staphylococcus aureus [PDF]

BioImpacts, 2015
Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) plays an important role in causing many serious nosocomial infections. In this study, the antimicrobial susceptibility and the frequency of aminoglycoside modifying enzyme encoding genes ...
Zahra Shokravi, Laleh Mehrad, Ali Ramazani   +2 more
doaj   +1 more source