Results 31 to 40 of about 6,008 (170)

Diversity of SCCmec elements in Staphylococci isolated from public washrooms [PDF]

BMC Microbiology, 2015
Staphylococci are commonly associated with antibiotic resistance in healthcare settings including resistance to methicillin and other beta lactam antibiotics primarily associated with the carriage of SCCmec mobile genetic elements. We investigated oxacillin susceptibility in 11 different species of environmental staphylococci to evaluate the potential ...
Mkrtchyan, Hermine, Xu, Zhen, Cutler, Ronald R.   +2 more
openaire   +3 more sources

Molecular Diversity and Comparison of Staphylococcal Cassette Chromosome mec Element in Hospital‐ and Community‐Associated Methicillin‐Resistant Staphylococcus aureus From Pakistan [PDF]

Int J Microbiol
Background Methicillin‐resistant Staphylococcus aureus (MRSA) is one of the leading causes of hospital and community‐acquired infections, with the increasing threat of antimicrobial resistance worldwide. Staphylococcal Cassette Chromosome mec (SCCmec) typing is one of the molecular techniques to predict the genetic background of MRSA strains and ...
Ali A, Jabbar S, Aziz S, Riaz S.
europepmc   +2 more sources

Associations between dru Types and SCCmec Cassettes

PLoS ONE, 2013
Molecular typing is an important tool in the investigation of methicillin resistant Staphylococcus aureus (MRSA) outbreaks and in following the evolution of MRSA. The staphylococcal cassette chromosome mec (SCCmec) contains a hypervariable region with a variable number of 40 bp repeats named direct repeat units (dru).
Bartels, Mette D., Boye, Kit, Oliveira, Duarte C., Worning, Peder, Goering, Richard, Westh, Henrik   +5 more
openaire   +5 more sources

A novel DNA primase-helicase pair encoded by SCCmec elements

eLife, 2020
Mobile genetic elements (MGEs) are a rich source of new enzymes, and conversely, understanding the activities of MGE-encoded proteins can elucidate MGE function. Here, we biochemically characterize three proteins encoded by a conserved operon carried by the Staphylococcal Cassette Chromosome (SCC mec
Bebel, Aleksandra, Walsh, Melissa A., Mir-Sanchis, Ignacio, Rice, Phoebe A.   +3 more
openaire   +5 more sources

Antibiotics trigger initiation of SCCmec transfer by inducing SOS responses [PDF]

Nucleic Acids Research, 2017
The rise of antimicrobial resistance limits therapeutic options for infections by methicillin-resistant staphylococci. The staphylococcal cassette chromosome mec (SCCmec) is a mobile genetic element as the only carrier of the methicillin-resistance determinants, the mecA or mecC gene. The use of antibiotics increases the spread of antibiotic resistance,
Liu, Pilong, Wu, Zhaowei, Xue, Huping, Zhao, Xin   +3 more
openaire   +2 more sources

Difference in agr dysfunction and reduced vancomycin susceptibility between MRSA bacteremia involving SCCmec types IV/IVa and I-III.

PLoS ONE, 2012
BackgroundDysfunction of agr, with reduced susceptibility or hetero-resistance to vancomycin, is thought to be associated with a worse outcome of methicillin-resistant Staphylococcus aureus (MRSA) bacteremia (MRSAB).
Hee-Chang Jang, Seung-Ji Kang, Su-Mi Choi, Kyung-Hwa Park, Jong-Hee Shin, Hyon E Choy, Sook-In Jung, Hong Bin Kim   +7 more
doaj   +1 more source

Molecular Evolutionary Pathways toward Two Successful Community-Associated but Multidrug-Resistant ST59 Methicillin-Resistant Staphylococcus aureus Lineages in Taiwan: Dynamic Modes of Mobile Genetic Element Salvages.

PLoS ONE, 2016
Clonal complex 59 (CC59) Staphylococcus aureus in Taiwan includes both methicillin-susceptible S. aureus (MSSA) and methicillin-resistant S. aureus (MRSA).
Wei-Chun Hung, Tsai-Wen Wan, Yu-Chia Kuo, Tatsuo Yamamoto, Jui-Chang Tsai, Yu-Tzu Lin, Po-Ren Hsueh, Lee-Jene Teng   +7 more
doaj   +1 more source

Novel rearrangements in the staphylococcal cassette chromosome mec type V elements of Indian ST772 and ST672 methicillin resistant Staphylococcus aureus strains. [PDF]

PLoS ONE, 2014
Staphylococcus aureus is a commensal gram positive bacteria which causes severe and non severe infections in humans and livestock. In India, ST772 is a dominant and ST672 is an emerging clone of Staphylococcus aureus.
Jayanth Balakuntla, Sushma Prabhakara, Gayathri Arakere   +2 more
doaj   +1 more source

Detection of sasX Gene and Distribution of SCCmec Types in Invasive and Non-invasive Coagulase-negative Staphylococci

Balkan Medical Journal, 2020
Background: Coagulase-negative staphylococci, which belong to the normal microbiota of the skin and mucous membranes, are opportunistic pathogens. sasX, a newly described protein, is thought to play an important role in nasal colonization and methicillin-
Alper Tekeli, Duygu Nilüfer Öcal, İştar Dolapçı   +2 more
doaj   +1 more source

Detecting the frequency of aminoglycoside modifying enzyme encoding genes among clinical isolates of methicillin-resistant Staphylococcus aureus [PDF]

BioImpacts, 2015
Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) plays an important role in causing many serious nosocomial infections. In this study, the antimicrobial susceptibility and the frequency of aminoglycoside modifying enzyme encoding genes ...
Zahra Shokravi, Laleh Mehrad, Ali Ramazani   +2 more
doaj   +1 more source