Results 61 to 70 of about 1,149 (185)

Fosmanogepix (APX001) Is Effective in the Treatment of Immunocompromised Mice Infected with Invasive Pulmonary Scedosporiosis or Disseminated Fusariosis. [PDF]

, 2020
There are limited treatment options for immunosuppressed patients with lethal invasive fungal infections due to Fusarium and Scedosporium Manogepix (MGX; APX001A) is a novel antifungal that targets the conserved Gwt1 enzyme required for localization of ...
Alkhazraji, Sondus, Alqarihi, Abdullah, Gebremariam, Teclegiorgis, Gu, Yiyou, Ibrahim, Ashraf S, Mamouei, Zeinab, Shaw, Karen J, Singh, Shakti, Wiederhold, Nathan P   +8 more
core   +1 more source

Monoclonal antibodies against peptidorhamnomannans of Scedosporium apiospermum enhance the pathogenicity of the fungus. [PDF]

PLoS Neglected Tropical Diseases, 2010
Scedosporium apiospermum is part of the Pseudallescheria-Scedosporium complex. Peptidorhamnomannans (PRMs) are cell wall glycopeptides present in some fungi, and their structures have been characterized in S. apiospermum, S.
Livia C L Lopes, Rodrigo Rollin-Pinheiro, Allan J Guimarães, Vera C B Bittencourt, Luis R Martinez, Wade Koba, Sandra E Farias, Joshua D Nosanchuk, Eliana Barreto-Bergter   +8 more
doaj   +1 more source

Phylogenetic Findings Suggest Possible New Habitat and Routes of Infection of Human Eumyctoma [PDF]

, 2013
Eumycetoma is a traumatic fungal infection in tropical and subtropical areas that may lead to severe disability. Madurella mycetomatis is one of the prevalent etiologic agents in arid Northeastern Africa.
Ahmed, S.A. (Sarah Abdalla), Eberhardt, U. (Ursala), Fahal, A.H. (Ahmed), Hoog, G.S. de, Keisari, M.S. (Maryam Saradeghi), Najafzadeh, M.J. (Mohammad), Sande, W.W.J. (Wendy) van de, Stielow, B. (Bastian), Sutton, D.A. (Deanna), Verkleij, S.P.J. (Saskia ), Xin, Z.T. (Zhong-Tao)   +10 more
core   +1 more source

Prognostic factors in 264 adults with invasive Scedosporium spp. and Lomentospora prolificans infection reported in the literature and FungiScope [PDF]

, 2019
Invasive Scedosporium spp. and Lomentospora prolificans infections are an emerging threat in immunocompromised and occasionally in healthy hosts. Scedosporium spp. is intrinsically resistant to most, L. prolificans to all the antifungal drugs currently
Aurbach U., Caggiano G., Chander J., Chedotal I., Cheng M. P., Cornely O. A., Denis J., Duarte R. F., Duran Graeff L., Hamprecht A., Herbrecht R., Kohler P., Lackner M., Los-Arcos I., Mares M., Meissner A., Mellinghoff S., Montagna M. T., Pakstis D. L., Piepenbrock E., Salmanton-Garcia J., Seidel D., Slavin M., Stecher M., Trauth J., Vehreschild J. J., Vehreschild M. J. G. T., Wisplinghoff H.   +27 more
core   +3 more sources

Scedosporiosis Transmission from Near-Drowning Donor to Kidney Recipient: A Case Report and Literature Review [PDF]

, 2022
Infection is a common complication following a near-drowning event. Near-drowning victims as organ donors carry an increased risk for donor-derived infection.
Kohli, MD, Romesh, Liu, MD, PhD*, Lin, Tomaszewski, MD, John E, Yang, MD, PhD, Bei   +3 more
core   +1 more source

Mucormycosis Leading to Cerebral Edema and Cerebellar Tonsillar Herniation after Allogeneic Bone Marrow Transplant: A Case Report

Case Reports in Infectious Diseases, Volume 2019, Issue 1, 2019., 2019
Introduction. Mucormycosis following hematopoietic stem cell transplant (HSCT) carries a very high mortality rate. Pulmonary mucormycosis often leads to systemic dissemination and eventual death. It is imperative for transplant providers to have a high level of suspicion for mucormycosis and initiate early treatment.
Chetan Jeurkar, Lauren Margetich, Ziver Sahin, Raul Colodner   +3 more
wiley   +1 more source

Pulmonary scedosporiosis–A rare entity

Asian Pacific Journal of Tropical Disease, 2011
Abstract Pulmonary scedosporiosis is a rare opportunistic fungal infection of the lungs in humans and mostly it occurs in previously diseased lungs or in immunocompromised patients. We report here a case of 30-year-old female who presented with complaints of cough with expectoration, breathlessness, chest pain and fever since one year ago and was ...
Sushant H Meshram, Gyanshankar P Mishra
openaire   +1 more source

Non-Aspergillus mould lung infections

European Respiratory Review, 2022
Non-Aspergillus filamentous fungi causing invasive mould infections have increased over the last years due to the widespread use of anti-Aspergillus prophylaxis and increased complexity and survival of immunosuppressed patients.
Pedro Puerta-Alcalde, Carolina Garcia-Vidal   +1 more
doaj   +1 more source

Recurrent Scedosporium apiospermum mycetoma successfully treated by surgical excision and terbinafine treatment: a case report and review of the literature [PDF]

, 2017
Background: Scedosporium apiospermum is an emerging opportunistic filamentous fungus, which is notorious for its high levels of antifungal ‑resistance.
A Harun, C Eldin, CH Chiang, CH Heath, CP Bower, Csaba Vágvölgyi, D Reimann, E Lemerle, Edit Urbán, Eszter J. Tóth, F Beier, F Bosma, F Gilgado, G Béraud, G Tarozzi, Gábor Nagy, Géza R. Nagy, I Tammer, I Tammer, I Valenzuela Salas, Ildikó É. Kiss, J Guarro, J Sopta, JV Pether, KJ Cortez, L Ajello, L Porte, L Török, LA Montero, Lajos Kemény, M Chen, M Lainščak, M Montejo, Marianna Ábrók, MI Taşbakan, Mónika Homa, PG Rogasi, R Cunningham, R Horré, S Giraud, SA Kantarcioğlu, Tamás Papp, TJ White, TT Ng, V Gulati, Zsuzsanna Bata-Csörgő   +45 more
core   +1 more source

The Role of Antifungals in Pediatric Critical Care Invasive Fungal Infections

Critical Care Research and Practice, Volume 2018, Issue 1, 2018., 2018
Invasive fungal infections (IFIs) have seen considerable increase in pediatric intensive care units over the past several decades. IFIs are predominantly caused by Candida species, and candidemia is the third most common cause of healthcare‐associated bloodstream infections (BSIs) in children.
Ashlesha Kaushik, Helen Kest, Robert Boots   +2 more
wiley   +1 more source