Peptidorhamnomannan negatively modulates the immune response in a scedosporiosis murine model. [PDF]
In this study, we analyzed the impact of immunization with the peptidorhamnomannan (PRM) from the cell wall of the fungus Scedosporium (Lomentospora) prolificans in a murine model of invasive scedosporiosis. Immunization with PRM decreased the survival of mice infected with S. prolificans. Immunization of mice with PRM led to decreased secretion of pro-
M. Xisto +9 more
semanticscholar +3 more sources
Molecular and cellular responses of the pathogenic fungus Lomentospora prolificans to the antifungal drug voriconazole [PDF]
The filamentous fungus Lomentospora (Scedosporium) prolificans is an emerging opportunistic pathogen associated with fatal infections in patients with disturbed immune function.
Antorán Díaz, Aitziber +5 more
core +4 more sources
A case of central nervous system infection with Scedosporium boydii
This research described a case of a man with brain abscesses infected with Scedosporium. boydii. It emphasized the importance of using multiple methods for early identification, including microscopy, culture combined with Matrix‐assisted laser desorption ionization time‐of‐flight mass spectrometry (MALDI‐TOF MS), internal transcribed spacer (ITS ...
Zhen Cai +4 more
wiley +1 more source
Scedosporium/Lomentospora fungi are increasingly recognized pathogens. As these fungi are resistant to many antifungal agents, early diagnosis is essential for initiating targeted drug therapy.
Sharon C.-A. Chen +4 more
doaj +1 more source
Posaconazole is the newest antifungal agent to be approved for use in Canada. With excellent in vitro activity against a broad spectrum of yeasts and filamentous fungi, as well as having a well‐tolerated oral formulation, posaconazole offers many potential advantages.
Andrea V Page, W Conrad Liles
wiley +1 more source
Two cases of severe pneumonia after the 2011 Great East Japan Earthquake
In 2011, during the Great East Japan Earthquake and tsunami, 90% of victims died from drowning. We report on two tsunami survivors with severe pneumonia potentially caused by Legionella pneumophila. Both victims aspirated a large quantity of contaminated
Shigeatu Endo +3 more
doaj +1 more source
Pharmacokinetics of voriconazole and posaconazole administered in experimental models of disseminated scedosporiosis with cerebral involvement [PDF]
International ...
A. Turcant +6 more
core +1 more source
New and emerging options for management of invasive fungal diseases in paediatric patients
Abstract Invasive fungal diseases (IFDs) play an important role in the supportive care of paediatric patients with acute leukaemia and those undergoing allogeneic haematopoietic cell transplantation, and they are associated with significantly decreased overall survival rates in affected individuals.
Andreas H. Groll +3 more
wiley +1 more source
Use of triazole antifungal drugs in setting up an animal model of cerebral scedosporiosis [PDF]
Scedosporium apiospermum is a soil fungus which may cause severe and often fatal cerebral mycosis in immunocompetent patients in the case of near drowning and in immunosuppressed patients such as lung transplant recipients.
B. Diquet +4 more
core +1 more source
Successful management of invasive aspergillosis with voriconazole and amphoteracin B therapy in a patient with acute mycloid leukemia (AML-M2) [PDF]
An eleven-year-old boy presented with one month\u27s history of fever and weight loss. He was diagnosed with Acute Mycloid Leukemia (AML-M2). During treatment he developed recurrent infections with neutropenia requiring prolonged antibiotics and ...
Azim, Sidra +2 more
core +1 more source

