Results 41 to 50 of about 123,614 (254)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier +11 more
wiley +1 more source
EngineeringScenario planning is a powerful tool for cities to navigate uncertainties and mitigate the impacts of adverse scenarios by projecting future outcomes based on present-day decisions.
Haiyan Hao, Yan Wang, Jiayu Chen
doaj +1 more source
Iterative scenarios for social-ecological systems
Ecology and Society, 2021 Managing social-ecological systems toward desirable regimes requires learning about the system being managed while preparing for many possible futures.
Dustin L. Herrmann +5 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Scenario planning methodology in biomedicine sciences
Iranian South Medical Journal, 2015 Scenario planning is a process that stimulates imaginative, creative thinking to better prepare an organization for the future. It is also as a tool to promote innovation activities in organizations.
Iraj Nabipour
doaj
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Scenario planning and nanotechnological futures [PDF]
European Journal of Physics, 2009 Scenario planning may assist us in harnessing the benefits of nanotechnology and managing the associated risks for the good of the society. Scenario planning is a way to describe the present state of the world and develop several hypotheses about the future of the world, thereby enabling discussions about how the world ought to be.
Farber, Darryl, Lakhtakia, Akhlesh
openaire +2 more sources
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
People and Nature, 2022 Envisioning processes enable protected area managers to chart a course for future management to reach desired goals, but unexpected changes that could affect future visions are not usually considered.
Veronica B. P. G. Lo +7 more
doaj +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source