Schematic illustration of resident macrophages in Immune checkpoint inhibitor‐associated nephrotoxicity (ICI‐AN). Using an integrated approach (including imaging mass cytometry, transcriptomics, and murine models), this study reveals that resident macrophages drive immune‐stromal interactions in ICI‐AN, promoting fibroblast activation through CXCL9 and
Yanhong Ma +11 more
wiley +1 more source
Decoding Handwriting Trajectories from Intracortical Brain Signals for Brain‐to‐Text Communication
By developing a novel framework that optimizes both shape and temporal loss during decoder training, the authors successfully reconstruct human‐recognizable handwriting trajectories from intracortical neural signals for both Chinese characters and English letters, effectively resolving the temporal misalignment problem in clinical BCIs, thereby ...
Guangxiang Xu +6 more
wiley +1 more source
One-step ahead: evaluating the efficacy of single-visit rabies pre-exposure prophylaxis against conventional multi-visit protocol: a randomized non-inferiority clinical trial. [PDF]
Singh AD +7 more
europepmc +1 more source
A Resistive Soft Robotic Exosuit for Dynamic Body Loading in Hypogravity
The resistive hypogravity exosuit is a lightweight wearable robotic exosuit that uses pneumatic artificial muscles to restore Earth‐like metabolic and muscular demands during locomotion in low gravity. Tested on healthy subjects in Earth and simulated Moon gravity, the suit restores energy expenditure and muscle activation without altering gait ...
Emanuele Pulvirenti +6 more
wiley +1 more source
Chaining Differential Reinforcement of Compliance and Functional Communication Training to Treat Challenging Behavior Maintained by Negative Reinforcement. [PDF]
Ferris EL +5 more
europepmc +1 more source
Hesperidin nanoparticles (HE NPs) effectively combat obesity and sleep‐disordered breathing in mice by enhancing leptin sensitivity. Through suppression of hypothalamic endoplasmic reticulum stress and restoration of leptin signaling, HE NPs promote weight loss and improve breathing during sleep.
Yixuan Wang +11 more
wiley +1 more source
Auditory-motor adaptation and de-adaptation for speech depend more on time in the new environment than on the amount of practice. [PDF]
Kim KS, Kitchen NM, Mitsuya T, Max L.
europepmc +1 more source
A personalized nanovaccine combining PLGA‐encapsulated heat‐inactivated CVB3 and membranes from CVB3‐infected breast cancer cells stimulates potent antitumor immunity. It reduces immunosuppressive markers, enhances immune activation, and improves survival in vivo.
Amirhossein Bahreyni +6 more
wiley +1 more source
Bridging the Gap: Two Decades of Childhood Vaccination Coverage and Equity in Cambodia and the Philippines (2000-2022). [PDF]
Zhang Y, Zhang X, Long Q.
europepmc +1 more source

