Results 231 to 240 of about 3,480,656 (399)

MRI-based digital twins to improve treatment response of breast cancer by optimizing neoadjuvant chemotherapy regimens. [PDF]

open access: yesNPJ Digit Med
Wu C   +8 more
europepmc   +1 more source

From Invaginating Site to Deep Lesion: Spatial Transcriptomics Unravels Ectopic Endometrial Penetration Features in Adenomyosis

open access: yesAdvanced Science, EarlyView.
This work utilizes spatial transcriptomics to map the transcriptional landscape of adenomyosis with obvious invagination structure from the invaginating site to deep lesions. By integrating with single‐cell RNA sequencing, this study elucidates the molecular features of invagination, invasion, and fibrosis, and finds the major participants and vital ...
Boyu Li   +19 more
wiley   +1 more source

A pilot randomized controlled trial of WeiNaoKang (SaiLuoTong) in treating vascular dementia

open access: yesAGING MEDICINE, Volume 5, Issue 4, Page 246-256, December 2022., 2022
A 16‐week randomized double‐blind, placebo‐controlled trial for vascular dementia was carried out with WeiNaoKang (or SaiLuoTong). There were significant differences in improvement in cognitive function and activities of daily living, favouring the treatment group.
Junguang Liu   +6 more
wiley   +1 more source

Cost-effectiveness analysis of alternative infant and neonatal rotavirus vaccination schedules in Malawi. [PDF]

open access: yesPLOS Glob Public Health
Wenger C   +10 more
europepmc   +1 more source

Orally Administered Functional Polyphenol‐Nanozyme‐Armored Probiotics for Enhanced Amelioration of Intestinal Inflammation and Microbiota Dysbiosis

open access: yesAdvanced Science, EarlyView.
This study presents a novel polyphenol‐nanozyme‐armored probiotic system (ECA@EcN) for enhanced treatment of inflammatory bowel disease (IBD). By integrating chitosan‐modified epigallocatechin gallate (EGCG‐CS) with gold nanozymes, the system effectively scavenges ROS, improves probiotic viability, and restores gut microbiota balance.
Yong Zhu   +12 more
wiley   +1 more source

An exposure-safety analysis to support the dosage of the novel AKT inhibitor capivasertib. [PDF]

open access: yesCancer Chemother Pharmacol
Teruel CF   +4 more
europepmc   +1 more source

ROS‐Activated Nanohydrogel Scaffolds with Multi‐Factors Controlled Release for Targeted Dual‐Lineage Repair of Osteochondral Defects

open access: yesAdvanced Science, EarlyView.
ROS‐activated nanohydrogels composite bilayer scaffolds are rationally designed for targted dual‐lineage repair of osteochondral defects. The as‐prepared nanohydrogel scaffolds provided 3D culture and induced dual‐lineage differentiation of BMSCs in vitro, efficiently inhibited early‐stage inflammation by rapidly releasing DS and improved cartilage and
Xiuhui Wang   +14 more
wiley   +1 more source

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