Results 231 to 240 of about 2,804,250 (299)

Randomized Phase 2 Trial of an Extended and Flexible Dosing Schedule of ¹⁷⁷Lu-PSMA Molecular Radiotherapy in Patients with Metastatic Castration-Resistant Prostate Cancer (FLEX-MRT): Study Protocol. [PDF]

J Nucl Med
Holzgreve A, Delker A, Ells Z, Brosch-Lenz J, Unterrainer LM, Nikitas J, Zhu S, Contreras MM, Alam H, Nabong RM, Lira S, Vasilyev A, Chen L, Grogan T, Elashoff D, Meyer CA, Dahlbom M, Czernin J, Calais J.   +18 more
europepmc   +1 more source

Open Access Week 2016 Event Schedule Poster [PDF]

, 2016
Newman, Anna
core   +1 more source

ZFPL1 Promotes Colorectal Cancer Progression by Stabilizing ASS1 to Drive the Urea Cycle and M2 Macrophage‐Mediated Metastatic Colonization

Advanced Science, EarlyView.
ScRNA‐seq reveals ZFPL1‐specific enrichment in malignant CRC cells. Mechanistically, ZFPL1 stabilizes ASS1 by blocking K57 ubiquitination, activating urea cycle metabolism to drive progression. ZFPL1 inhibition reprograms the TME by suppressing M2 macrophages polarization and promotion M1 macrophages, thereby inhibiting CRC liver metastasis ...
Xiangjun Qian, Chenxi Xie, Beilin Zhang, Hengsong Cao, Zhengqing Lu, Li Liu, Shipeng Dai, Xiaoqian Wang, Xiaokai Zhang, Feng Han, Yanyan Liu, Haibo Yu, Weiwei Tang, Jinxue Zhou, Xiaopei Hao   +14 more
wiley   +1 more source

An optimized novel lightweight block cipher for image encryption. [PDF]

Sci Rep
Mohanapriya R, Nithish KV.
europepmc   +1 more source

Forelimb Motor Learning and Memory Consolidation Drives Distinct Oligodendrocyte Plasticity to Regulate Task‐related Neuronal Activity

Advanced Science, EarlyView.
Genetic and chemical tracking of oligodendrogenesis, combining fiber photometric neuronal activity recording, reveals that distinct oligodendrocyte plasticities are adopted during different phases of motor learning to fine‐tune task‐related neuronal activity, with a preferential involvement of oligodendrogenesis suppression and node lengthening (type 2
Shuming Wang, Nuo Xu, Wenwen Wang, Yongxiang He, Yuqian Yang, Liuning Zhang, Yanping Zou, Yuehua He, Huiliang Li, Liang Gao, Lin Xiao   +10 more
wiley   +1 more source

Using Machine Learning to Predict-Then-Optimize Elective Orthopedic Surgery Scheduling to Improve Operating Room Utilization: Retrospective Study.

JMIR Med Inform
Lex JR, Abbas A, Mosseri J, Singh Toor J, Simone M, Ravi B, Whyne C, Khalil EB.   +7 more
europepmc   +1 more source

Multicriteria scheduling of two-subassembly products with batch availability and precedence constraints. [PDF]

PeerJ Comput Sci
Wen Z, Li S.
europepmc   +1 more source

Microglial Deletion of Hrh4 Alleviates Alzheimer's Disease Pathologies by Enhancing Microglial Phagocytosis of Amyloid‐β and Tau

Advanced Science, EarlyView.
Histamine H4 receptor (H4R) antagonist VUF6002 mimics low‐dose X‐ray irradiation in aged Alzheimer's disease (AD) mice, enhancing microglial clearance of amyloid‐beta/hyperphosphorylated tau aggregates and restoring cognition. Microglial H4R deletion activates cAMP/TGF‐β1/Smad3 pathway, enhancing phagocytosis, while TGF‐β receptor 1 deletion abolishes ...
Yi‐Jun Xu, Tan Wu, Larry Tso‐Lun Lo, Chi‐Chiu Ko, Xin Wang, Chi Him Eddie Ma   +5 more
wiley   +1 more source

Demographic and Clinical Characteristics of Patients Vaccinated Against Herpes Zoster in a Primary Care Setting in Spain: A Retrospective Study. [PDF]

Vaccines (Basel)
Blanc-Rodriguez-Arias JM, Jimeno-Sanz I, Hernández-Barrera V, Álvaro-Meca A, Torres-Ramos M, Gil-de-Miguel Á.   +5 more
europepmc   +1 more source

Interferon‐Driven Biomarkers and Synergistic Therapy for PRMT5 Inhibition in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Triple‐negative breast cancer exhibits variable sensitivity to PRMT5 inhibition. Basal interferon signaling is identified as a key biomarker of response. PARP inhibition with olaparib induces IFN signaling, sensitizing resistant TNBC cells to PRMT5 inhibitors.
Ziwen Zhang, Sheyu Zhang, Lu Guo, Yichun Pan, Juan Huang, Yishuai Ji, Jiaqi Tao, Yong Wei, Xiaojia Wang, Qin Wu   +9 more
wiley   +1 more source