Results 41 to 50 of about 535,286 (269)

Widening the Schedulability of Hierarchical Scheduling Systems [PDF]

, 2015
This paper presents a compositional approach for schedulability analysis of hierarchical systems, which enables to prove more systems schedulable by having richer and more detailed scheduling models. We use a lightweight method (statistical model checking) for design exploration, easily assuring high confidence in the correctness of the model.
Abdeldjalil Boudjadar, Alexandre David, Jin Hyun Kim, Kim Guldstrand Larsen, Marius Mikucionis, Ulrik Nyman, Arne Skou   +6 more
openaire   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

SPECIALIZED MODEL OF THE ASSIGNMENT PROBLEM FOR THE SCHEDULE OF ACTIVITIES OF HIGHER EDUCATION INSTITUTIONS

Nauka ta progres transportu, 2009
The method for modeling the creation of high school’s schedule as an assignment task with inhomogeneous parameters, and the basic directions of development are considered.
S. Yu. Razumov
doaj  

PARTICULARITIES OF DRIVER’S WORK AND REST SCHEDULE CONDITIONS IN ORGANIZED CHILDREN CARRIAGE IN INTERCITY CONNECTION

Вестник СибАДИ, 2020
Introduction. The article is devoted to the description of the shedule development particularities and a drivers’ work and rest schedule adjustment in an organized children carriage considering their age in an intercity connection.
O. E. Ianuchkova, M. R. Ianuchkov, N. V. Iakunina   +2 more
doaj   +1 more source

The Impact of the Learning and Forgetting Effect on the Cost of a Multi-Unit Construction Project with the Use of the Simulated Annealing Algorithm

Applied Sciences, 2022
Construction projects are often delayed. Their budgets are being exceeded. This is partly because construction project models rarely take human factors into account.
Michał Podolski, Jerzy Rosłon, Bartłomiej Sroka   +2 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Assessment of risks in construction [PDF]

Строительство уникальных зданий и сооружений, 2013
The realization of any investment project involves various types of risks, due to the presence of uncertainty in the economic activity of the enterprise. The reasons of occurrence risks are not the full amount of information about the future Distinction
Tatiana Fedorovna Morozova, Kinayat Laula Argenovna, Kinayat Ayan Zhaksibekuli   +2 more
doaj  

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Sustainable green construction management: schedule performance and improvement

Technological and Economic Development of Economy, 2014
Over the last few years, the green building movement in Singapore has leaped bountifully. While environmental sustainability for greener construction has been emphasized, rare research has been conducted to analyze performance of green construction ...
Bon-Gang Hwang, Lay Peng Leong, Young-Ki Huh   +2 more
doaj   +1 more source