Results 51 to 60 of about 2,865,182 (350)
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Sustainable green construction management: schedule performance and improvement
Technological and Economic Development of Economy, 2014 Over the last few years, the green building movement in Singapore has leaped bountifully. While environmental sustainability for greener construction has been emphasized, rare research has been conducted to analyze performance of green construction ...
Bon-Gang Hwang +2 more
doaj +1 more source
EDF-Like Scheduling for Self-Suspending Real-Time Tasks [PDF]
, 2021 Mario Günzel +2 more
openalex +1 more source
Modelling of firm offer from combined wind and hydro generations [PDF]
, 2019 This paper analyses the impact of a firm combined offer by wind and small hydro generators located in the river chain, with a view to address the intermittency of wind generators.
Chakrabarti, Bhujanga
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Scheduling Without Payments [PDF]
Theory of Computing Systems, 2011 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +4 more sources
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
TIME RESERVES DURING THE ORGANISATION OF FREIGHT TRAIN MOVEMENT ON SCHEDULE
Nauka ta progres transportu, 2015 Purpose. The article is devoted to the development of estimation methods of time reserves that should be formed at the train schedule and the schedule for the turnover of freight trains, required to ensure the sustained interaction of technological ...
D. M. Kozachenko +3 more
doaj +1 more source
Distributed personnel scheduling—negotiation among scheduling agents [PDF]
Annals of Operations Research, 2007 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Kaplansky, Eliezer, Meisels, Amnon
openaire +2 more sources
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source