Results 61 to 70 of about 786,683 (318)
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Preoperative prevalence of deep vein thrombosis in patients scheduled to have surgery for degenerative musculoskeletal disorders [PDF]
, 2021 Keigo Sato +6 more
openalex +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Online scheduling and project scheduling [PDF]
, 2009 This thesis presents new and improved scheduling algorithms for a number of scheduling problems. The first part of the thesis deals with two online-list scheduling problems, both with the objective to minimize the makespan. In these problems, the jobs arrive one by one and the decision maker has to irrevocably schedule the arriving job before the next ...
openaire +2 more sources
Frontiers in Behavioral Neuroscience, 2019 Reward expectation and time estimation are important for behavior and affect corticospinal excitability. This study investigated changes in corticospinal excitability during rewarded time-sensitive behavioral tasks.
Makoto Suzuki +3 more
doaj +1 more source
Container Scheduling Under ARINC 653 Scheduler Constraints
2023 26th Euromicro Conference on Digital System Design (DSD), 2023 The ARINC 653 standard defines an operating system functional interface for computing systems in avionics. Its partitioning concept offers a specific approach to spatial and temporal separation. Despite its simplicity and low number of context switch counts, the ARINC 653 scheduler is often under-utilized, particularly during IO-intensive partition ...
Onen, Mehmet Sirin, Yurdakul, Arda
openaire +2 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Precise makespan optimization via hybrid genetic algorithm for scientific workflow scheduling problem [PDF]
, 2023 Pablo Barredo, Jorge Puente
openalex +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
FEBS Open Bio, EarlyView.Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani +7 more
wiley +1 more source