Results 111 to 120 of about 1,449,308 (259)

Asymmetric Cu─N─Ru Bridgedsite Nanozyme‐Loaded Injectable Thermogel Boosts Cuproptosis‐Like Death for Multidrug‐Resistant Urinary Tract Infections

open access: yesAdvanced Science, EarlyView.
To address multidrug‐resistant urinary tract infections (MDR‐UTIs), we developed Cu‐ZIF8‐Ru nanozyme featuring an asymmetric Cu─N─Ru catalytic site. This unique structure enhances multienzyme‐mimetic activity, eradicating resistant bacteria by inducing a cuproptosis‐like death pathway through intracellular Cu2+ accumulation and energy depletion.
Guanlin Li   +9 more
wiley   +1 more source

Spaceport operations for deep space missions [PDF]

open access: yes
Space Station Freedom is designed with the capability to cost-effectively evolve into a transportation node which can support manned lunar and Mars missions.
Holt, Alan C.
core   +1 more source

Profiling Localized Immunomodulation and Drug Biodistribution within a Subcutaneous Vascularized Niche for Cell Transplantation

open access: yesAdvanced Science, EarlyView.
We studied how five common immunosuppressants behave when delivered directly to a transplant site instead of systemically. Using a vascularized implant for islet transplantation, we show that local delivery protects grafts, limits drug spread to the rest of the body, and produces distinct immune signatures.
Jocelyn Nikita Campa‐Carranza   +19 more
wiley   +1 more source

Airline schedule punctuality management

open access: yes, 1991
Airline schedule punctuality is a complex problem and one of the major concerns of the airline top management. Flight schedule disturbances may occur as delays and/or cancellations. There are many internal and external reasons for delays. These delays may propagate in the aircraft cycles and cause a large schedule disturbance.
openaire   +1 more source

Integrated Ultrasound Device for Precision Bladder Volume Monitoring via Acoustic Focusing and Machine Learning

open access: yesAdvanced Science, EarlyView.
We present a conformable wearable ultrasound patch for noninvasive bladder volume monitoring. A flexible PZT array combined with a concave acoustic lens concentrates acoustic energy and improves depth selectivity through the anterior pelvic wall.
Long Long Cao   +4 more
wiley   +1 more source

Optimization of tray inventory levels in hospitals from an integral perspective. [PDF]

open access: yesHealth Care Manag Sci
Bos H   +4 more
europepmc   +1 more source

Вебзастосунок «Schedule manager»

open access: yes
У сучасному світі, коли життя стає дедалі більш динамічним та насиченим, ефективне управління часом набуває критичного значення. Саме тому був розроблений новітній вебзастосунок – "Schedule manager". Це потужний інструмент для планування, організації та відстеження виконання різноманітних завдань і подій. Його інтуїтивний календарний інтерфейс дозволяє
openaire   +1 more source

Mapping CSC‐Mediated Ovarian Cancer Chemoresistance via CXCR4‐PET to Guide Precision Cisplatin Re‐Sensitization Therapy

open access: yesAdvanced Science, EarlyView.
CXCR4 functions as a potential cancer stem cell‐associated marker linked to chemoresistance in ovarian cancer, and an inhibitor of CXCR4, AMD3100, can enhance the cytotoxic response to cisplatin. Based on these findings, [68Ga]Ga‐Pentixafor positron emission tomography enables selective visualization of CXCR4‐high ovarian cancer, while AMD3100 combined
Lixia Feng   +12 more
wiley   +1 more source

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