Reprogramming the Immune Landscape of Inflammatory Breast Cancer
Inflammatory breast cancer is the most lethal subtype of breast cancer and is characterized by an immunosuppressive tumor microenvironment (TME) driven by a complex network of immune cells and inflammatory cytokines, contributing to its aggressiveness and treatment challenges. Immune checkpoint inhibitors, either alone or in combination, show potential
Verena Martinez‐Rodriguez +3 more
wiley +1 more source
Decision-making considerations for single-dose HPV vaccination, including drivers of schedule adoption or switch: insights from immunisation stakeholders in 19 low-income and middle-income countries. [PDF]
Rosser EN +6 more
europepmc +1 more source
Full‐Stack Architectures for Intelligent Brain‐Computer Interfaces
System‐level overview of brain–computer interfaces (BCIs), illustrating the integration of neural signal acquisition, wireless transmission, and adaptive decoding. Advanced electrode, tissue interfaces, energy‐efficient communication, and robust algorithms collectively enable stable signal quality, real‐time processing, and closed‐loop operation ...
Hee Kyu Lee +9 more
wiley +1 more source
Identifying types of non-pharmacological interventions administered by healthcare providers for older adults with neurocognitive disorders who have lower urinary tract symptoms: A scoping review. [PDF]
Ishikawa K, Kawada A, Kamei T.
europepmc +1 more source
An immunoregulatory hydrogel based on sodium ascorbate (SA)‐accelerated gelation and in situ self‐mineralization is prepared here. Such a hydrogel is constructed by mixing benzaldehyde‐ and cyanoacetate‐functionalized dextran with silver nitrate (AgNO3) and SA, enabling the ultrafast solidification and in situ self‐mineralization of silver ...
Xiaoya Ding +4 more
wiley +1 more source
Patterns of pregabalin misuse: Need for intervention. [PDF]
Sarvepalli T +3 more
europepmc +1 more source
AI‐Designed Cyclic Peptides Enable Controllable Modulation of the CD28 Immune Checkpoint
AI‐designed cyclic peptides enable controllable modulation of the CD28 immune checkpoint through reversible disruption of CD28‐CD80/CD86 interactions. The lead peptide, CIP‐3, suppresses T‐cell activation without intrinsic agonist activity, demonstrates dose‐dependent efficacy in a murine colitis model, and attenuates inflammatory cytokine production ...
Katarzyna Kuncewicz +4 more
wiley +1 more source
Managing your life as an IR - perspective of a young IR. [PDF]
Grbanović L, Alduk AM.
europepmc +1 more source
Lessons From Drug Discovery for Cryoprotective Agent Design: An AI‐Oriented Perspective
Cryoprotectant design is reframed through the lens of drug discovery as a multiparameter optimization problem. This perspective highlights how AI and systematic design strategies could enable safer, more effective cryoprotectants, while identifying key limitations that currently constrain predictive progress in cryobiology. ABSTRACT Cryopreservation is
Dominika Wilczok +4 more
wiley +1 more source
Cost-effectiveness of integrated behavioral health for depression, anxiety, and chronic pain. [PDF]
Xuan D +3 more
europepmc +1 more source

