Results 141 to 150 of about 1,463,564 (259)
A lean way of design and production for healthcare construction projects [PDF]
As a consequence of the lack of solid conceptual foundation, the project management concepts and techniques usually applied within the construction sector are fragmented and have proved to be incapable of solving the complex problems of design ...
Codinhoto, Ricardo +3 more
core
Advanced Science, EarlyView.Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang +11 more
wiley +1 more source
Satellite power systems program [PDF]
The Department of Energy and NASA are engaged in an intense three-year analysis to determine what course of action the Federal government should pursue relative to this nonconventional energy system. Information is presented in the form of charts for the
Larock, R. I.
core +1 more source
Learnable Diffusion Framework for Mouse V1 Neural Decoding
Advanced Science, EarlyView.We introduce Sensorium‐Viz, a diffusion‐based framework for reconstructing high‐fidelity visual stimuli from mouse primary visual cortex activity. By integrating a novel spatial embedding module with a Diffusion Transformer (DiT) and a synthetic‐response augmentation strategy, our model outperforms state‐of‐the‐art fMRI‐based baselines, enabling robust
Kaiwen Deng +2 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Intestinal ischemia/reperfusion (I/R) injury presents a biphasic pathology: an acute oxidative‐inflammatory phase leading to organ failure, and a recovery phase marked by mucosal dysfunction and bacterial translocation. The developed MPB@TA‐Cu‐Ma nanocomposite functions as a dual‐phase therapeutic platform with significant efficacy. It rapidly
Chenghao Qiu +15 more
wiley +1 more source
Description of the computations and pilot procedures for planning fuel-conservative descents with a small programmable calculator [PDF]
A simplified flight management descent algorithm was developed and programmed on a small programmable calculator. It was designed to aid the pilot in planning and executing a fuel conservative descent to arrive at a metering fix at a time designated by ...
Knox, C. E., Vicroy, D. D.
core +1 more source
Advanced Science, EarlyView.We studied how five common immunosuppressants behave when delivered directly to a transplant site instead of systemically. Using a vascularized implant for islet transplantation, we show that local delivery protects grafts, limits drug spread to the rest of the body, and produces distinct immune signatures.
Jocelyn Nikita Campa‐Carranza +19 more
wiley +1 more source
Development of an estimation formula for preparation time of anesthesia induction and surgery accounting for clinical department factors in optimal surgery schedule management. [PDF]
Sci RepHara K +7 more
europepmc +1 more source
Advanced Science, EarlyView.We developed the enzyme‐responsive peptide SAp‐CD28 to selectively target CD28‐overexpressing T‐ALL cells. Following phosphatase‐mediated activation, SAp‐CD28 undergoes conformational switching and nanooligomerization, resulting in the disruption of CD28 downstream signaling.
Jun Li +10 more
wiley +1 more source
Contractors’ Approaches to Risk Management at the Construction Phase in Malaysia [PDF]
- Often times, contractors failed to identify, plan, strategize, analyzed, execute, monitor, control and manage the risk involves during construction phase in Malaysia.
Adnan, Hamimah +2 more
core +1 more source