Results 131 to 140 of about 155,764 (269)
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Optimizing vaccination scheduling during influenza outbreaks: a SEIAR-based model for balancing routine and emergency vaccination demands. [PDF]
Ma X, Huang Q, Chai S, Yin B.
europepmc +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Embree, Joanne, Tan, Ben
openaire +3 more sources
An open-source optimization model for sustainable open-pit mine production scheduling. [PDF]
Lotsu JS, Bimpong GY, Boakye K.
europepmc +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
The Power of Scheduling: the Scheduling of Power
Because of the ongoing energy transition, an increasing share of our energy needs is met by electrical energy. At the same time, more and more of this electricity is generated by renewable sources that strongly depend on the weather for their output. This is already causing issues on the Dutch electrical grid.
openaire +3 more sources
Radiology appointment management in German hospitals: a survey of referring physicians. [PDF]
Reschke P +11 more
europepmc +1 more source
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Tensor language model enables generative scheduling for efficient tensor compilation. [PDF]
Mehmood S +7 more
europepmc +1 more source

