Results 221 to 230 of about 1,347,718 (326)

Real-Time Scheduling for GPUs with Applications in Advanced Automotive Systems

, 2019
Glenn A. Elliott
openalex   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Collaborative scheduling of dual-trolley quay cranes and AGVs via speed-control strategy. [PDF]

PLoS One
Tan Y, Yan F, Zhang X, Yang L, Ma F, Wu Q.   +5 more
europepmc   +1 more source

Global sensitivity analysis and model-based reactive scheduling of targeted cancer immunotherapy

, 2010
Kanchi Lakshmi Kiran, S. Lakshminarayanan   +1 more
openalex   +2 more sources

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Research on deep learning architecture optimization method for intelligent scheduling of structural space. [PDF]

Sci Rep
Ying W, Hui L.
europepmc   +1 more source

Mapping and Scheduling Spiking Neural Networks On Segmented Ladder Bus Architectures

Phu Khanh Huynh, Francky Catthoor, Anup Das   +2 more
openalex   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

NF-MORL: a neuro-fuzzy multi-objective reinforcement learning framework for task scheduling in fog computing environments. [PDF]

Sci Rep
Yu X, Tang L, Mi J, Long L, Qin X, Li X, Mo Q.   +6 more
europepmc   +1 more source

Timed petri-net based formulation and an algorithm for the optimal scheduling of batch plants

, 2003
Tianlong Gu, Parisa A. Bahri, Guoyong Cai   +2 more
openalex   +1 more source