Results 71 to 80 of about 89,645 (310)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

A polynomial algorithm for special case of the one-machine scheduling problem with time-lags [PDF]

open access: yes
The standard one-machine scheduling problem consists in scheduling a set of jobs in one machine which can handle only one job at a time, minimizing the maximum lateness.
Helena Ramalhinho-Lourenço
core  

Sistem Penjadwalan Pertandingan Pencak Silat Berbasis Algoritma Genetika

open access: yesIJCCS (Indonesian Journal of Computing and Cybernetics Systems), 2017
Genetic Algorithm is one of famous algorithm and often used in many sector. Usually genetic algoritm is used in solution searching about complex problems. Pencak silat macth scheduling is a complex scheduling and needs a lot of time to made it. Objective
Ari Kusuma Wardana, Sri Hartati
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Power systems generation scheduling and optimisation using evolutionary computation techniques

open access: yes, 1996
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Optimal generation scheduling attempts to minimise the cost of power production while satisfying the various operation constraints and physical limitations ...
Orero, S.O, Orero, Shadrack Otieno
core  

Comparison Performance of Genetic Algorithm and Ant Colony Optimization in Course Scheduling Optimizing

open access: yesScientific Journal of Informatics, 2016
Scheduling problems at the university is a complex type of scheduling problems. The scheduling process should be carried out at every turn of the semester's. The core of the problem of scheduling courses at the university is that the number of components
Imam Ahmad Ashari   +2 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

An intelligent manufacturing system for heat treatment scheduling

open access: yes, 2010
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This research is focused on the integration problem of process planning and scheduling in steel heat treatment operations environment using artificial ...
Al-Kanhal, Tawfeeq
core  

A comparison of classical scheduling approaches in power-constrained block-test scheduling [PDF]

open access: yes, 2000
Classical scheduling approaches are applied here to overcome the problem of unequal-length block-test scheduling under power dissipation constraints. List scheduling-like approaches are proposed first as greedy algorithms to tackle the fore mentioned ...
Wang, Xiaojun   +6 more
core   +1 more source

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