Results 61 to 70 of about 273,738 (287)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Multi‐organization scheduling approximation algorithms [PDF]
Concurrency and Computation: Practice and Experience, 2011 SUMMARYIn this paper we consider the problem of scheduling on computing platforms composed of several independent organizations, known as the Multi‐Organization Scheduling Problem (MOSP). Each organization provides both resources and jobs and follows its own objectives.
Cohen, Johanne +3 more
openaire +3 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Learning Scheduling Algorithms for Data Processing Clusters
, 2019 Efficiently scheduling data processing jobs on distributed compute clusters requires complex algorithms. Current systems, however, use simple generalized heuristics and ignore workload characteristics, since developing and tuning a scheduling policy for ...
Abadi Martín +20 more
core +1 more source
Building Better Nurse Scheduling Algorithms [PDF]
Annals of Operations Research, 2004 The aim of this research is twofold: Firstly, to model and solve a complex nurse scheduling problem with an integer programming formulation and evolutionary algorithms. Secondly, to detail a novel statistical method of comparing and hence building better scheduling algorithms by identifying successful algorithm modifications.
Aickelin, U, White, P
openaire +10 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Research progress of mimic multi-execution scheduling algorithm
Tongxin xuebao, 2021 Mimic defense is the new active defense technology based on the dynamic heterogeneous redundant architecture.With inherent uncertainty, heterogeneous, redundant and negative feedback features, it can significantly improve the robustness and security of ...
Zhengbin ZHU +3 more
doaj +2 more sources
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Research on Task Priority Model and Algorithm for Satellite Scheduling Problem
IEEE Access, 2019 In satellite scheduling system, one of the most important issues is task scheduling. Most of the existing algorithms focused on the scenario of normal tasks with fixed priority and don’t consider emergency tasks.
Jian Wu +3 more
doaj +1 more source