Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
A New Framework for Job Shop Integrated Scheduling and Vehicle Path Planning Problem. [PDF]
Li R, Mao J, Wu X, Zhou W, Qian C, Du H.
europepmc +1 more source
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Distributed Integrated Scheduling Algorithm for Identical Two-Workshop Based on the Improved Bipartite Graph. [PDF]
Wei Y, Zhou W, Zhao J, Tan Z, Xie Z.
europepmc +1 more source
Irrigation schedules and production of processed tomatoes on the San Joaquin Westside
F Aljibury, D May
openalex +1 more source
Demand-side management via optimal production scheduling in power-intensive industries: The case of metal casting process [PDF]
Danial Ramin +2 more
openalex +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Inverse scheduling method for aircraft flat-tail assembly production based on improved genetic algorithm. [PDF]
Li T, Hua M, Wang J, Qin W.
europepmc +1 more source
Hybrid Multi objective Scheduling for a sheet production process with equipment exchange
Hiroshi Morita +2 more
openalex +2 more sources
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source

