Results 211 to 220 of about 241,676 (345)

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Fuzzy-based multi-objective scheduling for human-robot manufacturing systems. [PDF]

Sci Rep
Deng Y, Huang B, Lai S.
europepmc   +1 more source

Contract net protocol for cooperative optimisation and dynamic scheduling of steel production [PDF]

, 2003
D Ouelhadj, F Maturana, GY Lin, HV Parunak, JM Shaw, P Sousa, PI Cowling, PI Cowling, R Smith, S Weiming, W Sandholm Tuomas   +10 more
core   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Cell formation in real manufacturing systems with complex flow and technological constraints. [PDF]

Sci Rep
Petrini G, Sagawa JK.
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

​​Classified modeling and day-ahead optimal scheduling of multi-type adjustable industrial loads in industrial microgrid using improved approximate dynamic programming. [PDF]

Sci Rep
Sun T, Yang P, Sun Y, Luo X, Lu J, Duan K.   +5 more
europepmc   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

An improved artificial bee colony algorithm with path relinking strategy for the integrated distributed no-wait flow-shop scheduling and vehicle routing problem. [PDF]

Sci Rep
Dong C, Zhang H.
europepmc   +1 more source

THE APPLICATION OF A STOCKPILE STOCHASTIC MODEL INTO LONG-TERM OPEN PIT MINE PRODUCTION SCHEDULING TO IMPROVE THE FEED GRADE FOR THE PROCESSING PLANT

, 2020
Javad Gholamnejad, Ali Azimi, Reza Lotfian, Sara Kasmaeeyazdi, Francesco Tinti   +4 more
openalex   +1 more source