Results 51 to 60 of about 16,965 (263)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Applied Sciences, 2019 Since the concept of Industry 4.0 emerged, an increasing number of major manufacturers have incorporated relevant technologies to monitor machinery and schedule processes so as to increase yield and optimize production. However, most machinery monitoring
Yi-Chung Chen +5 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Proceedings of the International Conference on Applied Innovations in IT, 2020 The relevance of the problem is related to the necessity of improving production systems economical efficiency in constantly changing market conditions and their rivals' behaviour. In the article, it is suggested to use predictions that include diffusion
Leonid Mylnikov +2 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Artificial Intelligence overview for optimizing production scheduling in a picture framing company
Technical TransactionsArtificial Intelligence is significantly transforming manufacturing and impacting warehouse planning, production, operations, and logistics. This article explores AI applications in these areas, analyzing its role in optimizing scheduling and comparing ...
Krupnik-Worek Jadwiga +2 more
doaj +1 more source
Journal of Applied Engineering and Technological ScienceThis study aims to develop a digitalized scheduling system based on the Flexible Job Shop (FJS) model to optimize production efficiency in the heavy equipment manufacturing industry.
Mohammad Alfin Karim +1 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Scientific ReportsAircraft flat-tail assembly is a complex process that involves multiple assembly processes, multiple parallel frames, and multi-configuration mixed flow assembly, and its assembly processes exhibit extended processing times (typically measured in days ...
Tengda Li +3 more
doaj +1 more source