Results 121 to 130 of about 1,289,331 (411)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Object Oriented Approach for Integration of Heterogeneous Databases in a Multidatabase System and Local Schemas Modifications Propagation [PDF]

International Journal of Computer Science and Information Security, IJCSIS, Vol. 6, No. 2, pp. 055-060, November 2009, USA, 2009
One of the challenging problems in the multidatabase systems is to find the most viable solution to the problem of interoperability of distributed heterogeneous autonomous local component databases. This has resulted in the creation of a global schema over set of these local component database schemas to provide a uniform representation of local ...
arxiv  

Does schema therapy change schemas and symptoms? A systematic review across mental health disorders

Psychology and psychotherapy, 2016
Purpose Schema therapy was first applied to individuals with borderline personality disorder (BPD) over 20 years ago, and more recent work has suggested efficacy across a range of disorders.
C. Taylor, P. Bee, G. Haddock
semanticscholar   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

A Cognitive Approach to Tantric Language

Religions, 2016
By applying the contemporary theories of schema, metonymy, metaphor, and conceptual blending, I argue in this paper that salient cognitive categories facilitate a deeper analysis of Tantric language.
Sthaneshwar Timalsina
doaj   +1 more source

Schema Inference for Massive JSON Datasets

International Conference on Extending Database Technology, 2017
Recent years have seen the widespread use of JSON as a data format to represent massive data collections. JSON data collections are usually schemaless.
M. Baazizi, Houssem Ben Lahmar, Dario Colazzo, G. Ghelli, C. Sartiani   +4 more
semanticscholar   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Courage to Trust–Discussion of Moral Personality Built on the Confucian Ethics

Ethics in Progress, 2015
The value of Xin can find its origin in the Analects and other works by Confucius. Taking the perspectives from ethics and social psychology, pills  this research aims to probe possible psychological basis for the value of Xin and discuss it from two ...
Lei Kang, Ying Qiu, Tie Zheng, Anne Rubienska   +3 more
doaj   +1 more source

Type Safety with JSON Subschema [PDF]

arXiv, 2019
JSON is a popular data format used pervasively in web APIs, cloud computing, NoSQL databases, and increasingly also machine learning. JSON Schema is a language for declaring the structure of valid JSON data. There are validators that can decide whether a JSON document is valid with respect to a schema.
arxiv  

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source