Results 51 to 60 of about 648,597 (288)
Tridimensional model of CBT: a transdiagnostic and transtheoretical pragmatic model
Frontiers in PsychologyCognitive Behavioral Therapies (CBT) essentially represent an umbrella concept. Behavioral and cognitive (schema) theories form the foundation of all CBT approaches.
Kadir Özdel, Mehmet Hakan Turkcapar
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The Metaphor of Time as Moving through Locations in Sohrab Sepehri’s Poems Based on the Contemporary Theory of Metaphor [PDF]
مطالعات زبانها و گویشهای غرب ایران, 2016 Metaphor is one of the most important linguistic phenomena that has attracted the attention of philosophers, scholars, and recently linguists as well. Using advantages of the contemporary theory of metaphor introduced by Lakoff in 1992, the current study
Hamidreza Akbari, Leila Salehnejad
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Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Taḥqīqāt-i ̒Ulūm-i Raftārī, 2021 Aim and Background: Today, marriage is not simply as past, and young people on the verge of marriage suffer from a fear or concern about marriage and its issues that related to cognitive distortions, maladaptive schemas and coping styles that individuals
Samaneh Mokhtari +2 more
doaj
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Factor structure of the Young Positive Schema Questionnaire in an eating disorder sample [PDF]
, 2023 Tyrone Huckstepp +4 more
openalex +1 more source