Results 111 to 120 of about 3,861,665 (292)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

A mediating role of interpersonal sensitivity in the relationship between schematic mentalities and incompatible conflict resolution in single-parent women [PDF]

مجله علوم روانشناختی
Background: Schema modes, as stable patterns of thoughts, feelings, and behaviors formed during childhood, play a fundamental role in how individuals cope with conflicts.
negar razeghi, akram dehghani, shahrbanoo Ghahari, abbas haghayegh   +3 more
doaj  

“I feel [so alone] nothing” – emotional vulnerability and detachment as transdiagnostic key characteristics of patients with chronic tinnitus: a schema mode model approach

Frontiers in Psychiatry
BackgroundGold-standard approaches for chronic tinnitus involve hearing amplification measures and psychological therapy, where applicable. Whilst schema therapy is accumulating evidence as a transdiagnostically useful treatment framework, its ...
Benjamin Boecking, Petra Brueggemann, Birgit Mazurek   +2 more
doaj   +1 more source

The effectiveness of individual schema therapy in older adults with borderline personality disorder: Protocol of a multiple-baseline study

Contemporary Clinical Trials Communications, 2019
Background: The treatment of borderline personality disorder (BPD) has been examined extensively in adults up to the age of fifty in the past quarter of a century, but there is still a world to discover in treating BPD in older adults.
D.A. Khasho, S.P.J. van Alphen, S.M.J. Heijnen-Kohl, M.A. Ouwens, A. Arntz, A.C. Videler   +5 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Short-term group schema therapy for mixed personality disorders: A pilot study

Frontiers in Psychology, 2015
Schema Therapy has shown promising results for personality disorders but there is a limited evidence base for group Schema Therapy (ST-g) with mixed personality disorders.
Sally Ann Skewes, Rachel Anne Samson, Susan G Simpson, Michiel evan Vreeswijk   +3 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Combatting comorbidity: the promise of schema therapy in substance use disorder treatment

Discover Psychology
This paper explores the bidirectional relationship between trauma and Substance Use Disorders (SUDs), emphasising the need for integrated treatment approaches.
Daniel Talbot, Logan Harvey, Victoria Cohn, Melanie Truscott   +3 more
doaj   +1 more source

Figures of interpretation [PDF]

, 2009
This peer-reviewed article was intended to contribute to the general pedagogy of practice-led doctoral research through addressing the particular methodological issue of the relationship between written text and practice.
Rahtz, Dominic
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source