Results 51 to 60 of about 3,861,665 (292)

Factorial Structure and Preliminary Validation of the Schema Mode Inventory for Eating Disorders (SMI-ED)

open access: yesFrontiers in Psychology, 2018
Objective: The aim of this study was to examine the psychometric properties and factorial structure of the Schema Mode Inventory for Eating Disorders (SMI-ED) in a disordered eating population.Method: 573 participants with disordered eating patterns as ...
Susan G. Simpson   +13 more
doaj   +1 more source

Understanding the phenomenological experiences of schema therapy for those with an eating disorder

open access: yesQualitative Research in Medicine & Healthcare
Schema therapy expands traditional cognitive-behavioral models, weakening early maladaptive schemas and schema modes while strengthening adaptive modes.
Alice Cunningham   +3 more
doaj   +1 more source

Substantivism about truth [PDF]

open access: yes, 2016
Substantivism is a general philosophical methodology advocating a substantive approach to philosophical theorizing. In this article, I present an overview of this methodology with a special emphasis on the field of truth.
Sher, Gila
core   +1 more source

Psychometric Properties of Persian Version of Short Schema Mode Inventory

open access: yesEast Asian Archives of Psychiatry, 2021
To assess the psychometric properties of the Persian version of the short Schema Mode Inventory (SMI).The short SMI was translated into Persian by three clinical psychology professors and then back-translated into English by two professors in English language.
S, Ghahari   +3 more
openaire   +3 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

TEMPOS: A Platform for Developing Temporal Applications on Top of Object DBMS [PDF]

open access: yes, 2004
This paper presents TEMPOS: a set of models and languages supporting the manipulation of temporal data on top of object DBMS. The proposed models exploit object-oriented technology to meet some important, yet traditionally neglected design criteria ...
Dumas Menjivar, Marlon   +2 more
core   +3 more sources

Practical Representation [PDF]

open access: yes, 2020
This chapter discusses recent attempts to clarify the notion of practical representation and its theoretical fruitfulness. The ultimate goal is not just to show that intellectualists are on good grounds when they appeal to practical representation in ...
Pavese, Carlotta
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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