Results 91 to 100 of about 274,555 (304)

Comparison of the efficacy of acceptance and commitment-based therapy and schema therapy on self-efficacy and craving for change in addicts

open access: yesمجله علوم روانشناختی, 2021
Background: Studies have shown that low self-efficacy and poor beliefs in abilities in stressful situations are two causes of substance abuse and relapse of addictive behaviors.
Fatemeh Bahram Abadian   +2 more
doaj  

The Effectiveness of Schema Mode Therapy on Kind of Schema Process (in Mate-Selection) and Marriage Expectations in Girls In The Pre-marital Stage in Isfahan City [PDF]

open access: yesپژوهش‌های علوم شناختی و رفتاری
The present study aimed to evaluate the effectiveness of schema mode therapy on the kind of schema process (in mate selection) and marriage expectations among girls in the pre-marital stage in Isfahan. The research design was a semi-experimental pre-test
Maedeh Sarshoghi   +2 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

A set of ontologies to drive tools for the control of vector-borne diseases [PDF]

open access: yes, 2009
We are developing a set of ontologies that deal with vector-borne diseases and the arthropod vectors that transmit them. For practical reasons (application priorities), we initiated this project with an ontology of insecticide resistance followed by a ...
Christos Louis   +5 more
core   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Design and implementation of a federated health record server [PDF]

open access: yes, 2001
This paper describes the practical implementation of a federated health record serverbased on a generic and comprehensive public domain architecture and deployed in alive clinical setting.The authors, working at the Centre for Health Informatics and ...
Austin, A   +5 more
core  

Dangerous ontologies: the ethos of survival and ethical theorising in international relations [PDF]

open access: yes, 2002
The article responds to a recent call for a more systematic interrogation of the persistence of the dichotomous relation between ethics and International Relations.
Odysseos, Louiza
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

The effect of schema therapy on reducing symptoms of anxiety and depression in nursing and midwifery students

open access: yesJournal of Medical Education and Development, 2015
Introduction: Schema therapy is an important treatment method for cognitive disorders. This study aimed to examine the effect of education schema therapy in reducing symptoms of anxiety and depression in nursing and midwifery students.
Z Maleki, I Naderi, J Ashoori, O Zahedi
doaj  

Combatting comorbidity: the promise of schema therapy in substance use disorder treatment

open access: yesDiscover Psychology
This paper explores the bidirectional relationship between trauma and Substance Use Disorders (SUDs), emphasising the need for integrated treatment approaches.
Daniel Talbot   +3 more
doaj   +1 more source

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