Results 91 to 100 of about 198,870 (287)

The effect of schema therapy on reducing symptoms of anxiety and depression in nursing and midwifery students

open access: yesJournal of Medical Education and Development, 2015
Introduction: Schema therapy is an important treatment method for cognitive disorders. This study aimed to examine the effect of education schema therapy in reducing symptoms of anxiety and depression in nursing and midwifery students.
Z Maleki, I Naderi, J Ashoori, O Zahedi
doaj  

Combatting comorbidity: the promise of schema therapy in substance use disorder treatment

open access: yesDiscover Psychology
This paper explores the bidirectional relationship between trauma and Substance Use Disorders (SUDs), emphasising the need for integrated treatment approaches.
Daniel Talbot   +3 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Emotional Schema Therapy improves emotion regulation in individuals with a history of child abuse and neglect

open access: yes, 2019
Research conducted over the past decade indicates that difficulties in emotion regulation are more prevalent among those who have been abused than in individuals with no such experiences.
Wilson, Lee-Ann   +3 more
core   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

A mixed methods study of schema modes amongst people living with eating disorders

open access: yesJournal of Eating Disorders
Background Schema therapy is promising for people with eating disorders, especially those unresponsive to cognitive behavioural therapy. Complex underlying psychological constructs include dysfunctional schemas and maladaptive modes.
Clare Marney, Marie Reid, Bernice Wright
doaj   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

From the theoretical reformulation of the Schema Therapy model to the development of the Schema Mode Inventory-3: the Italian iterative process

open access: yes
reservedDati i recenti sviluppi teorici del modello Schema Therapy, l’Università di Amsterdam, nel 2022, ha avviato un progetto internazionale finalizzato all’ampliamento e alla validazione cross-culturale dei questionari diagnostici usati in Schema ...
INCERTI VEZZANI, CAMILLA
core  

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