Results 71 to 80 of about 18,431 (234)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
PSYNDEX Tests Review für FAMOS - Fragebogen zur Analyse Motivationaler Schemata
, 2003 This is a PSYNDEX Tests Review of FAMOS - Fragebogen zur Analyse Motivationaler Schemata. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries.
Wolff, Jutta
core +1 more source
KOGNITÍVNE SKRESLENIA AKO SÚČASŤ SPRISAHANECKÝCH TEÓRIÍ [PDF]
Slovenský Národopis, 2015 The beginnings of modern Greek philosophy have already indicated that man is not a reliable information processor, because he is unable to completely encompass the real world at a cognitive level.
Imrich Ruisel
doaj
On the Minimization Problem for Sequential Programs
Моделирование и анализ информационных систем, 2017 First-order program schemata is one of the simplest models of sequential imperative programs intended for solving verification and optimization problems.
Vladimir A. Zakharov +1 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
, 2018 Causal inferences about sparsely observed objects are often supported by causal schemata, or systems of abstract causal knowledge. We present a hierarchical Bayesian framework that learns simple causal schemata given only raw data as in- put. Given a set
Charles Kemp (3882901) +2 more
core +1 more source
On the Nature of the Conceptual Schemata Development of Architecture Students
Iconarp International Journal of Architecture and Planning, 2019 Embedded within the theoretical and conceptual frameworks implied by the schemata theory and studies on architectural precedent knowledge, the present study is based on a research that investigates and evaluates two major issues within the context of ...
Hakan Anay, Ülkü Özten
doaj +1 more source