Results 41 to 50 of about 8,289 (203)

Stabilizing Plasmodium falciparum proteins for small molecule drug discovery

open access: yesProtein Science, Volume 35, Issue 6, June 2026.
Abstract Early‐stage drug discovery relies on the availability of stable protein for reliable biophysical characterization of ligand binding. However, many Plasmodium falciparum proteins are challenging to produce in heterologous systems, which limits their experimental utility.
Marius Amann   +3 more
wiley   +1 more source

Radiological Loco‐Regional Treatments for Cholangiocarcinoma: A Systematic Review of the Literature

open access: yesLiver International, Volume 46, Issue 4, April 2026.
ABSTRACT Cholangiocarcinoma (CCA) is the second most common primary liver cancer and is being diagnosed with increasing frequency worldwide. We performed a systematic review on radiofrequency (RFA), microwave (MWA), irreversible electroporation (IRE), trans‐arterial chemoembolization (TACE) and selective internal radiation therapy (SIRT) in CCA. Thirty‐
Dimitrios Pallas   +6 more
wiley   +1 more source

Pedicle Subtraction Osteotomies for Correcting Sagittal Imbalance

open access: yesEgyptian Spine Journal, 2012
Background Data: Restoration of sagittal balance typically involves Smith Peterson osteotomy (SPO) or pedicle subtraction osteotomy (PSO). Since 2008, PSO was used for patients with kyphosis at our centers. Purpose: The aim of this study is to report the
Mohammad El-Sharkawi   +3 more
doaj   +1 more source

Providing a Realist Perspective on the eyeGENE Database System [PDF]

open access: yes, 2009
One of the achievements of the eyeGENE Network is a repository of DNA samples of patients with inherited eye diseases and an associated database that tracks key elements of phenotype and genotype information for each patient.
Werner Ceusters
core   +2 more sources

Effect of hypoxia on muscle activation at equivalent absolute and relative intensity during incremental and constant load exercise to task failure

open access: yesExperimental Physiology, Volume 111, Issue 4, Page 1933-1947, 1 April 2026.
Abstract We examined the impact of moderate hypoxia (HYPO) on muscle activation during incremental exercise matched for both absolute and equivalent relative intensity. Fifteen active subjects (10 males, 5 females) completed two ramp incremental test and two step tests in normoxia (NORM; FiO2${F_{{\mathrm{i}}{{\mathrm{O}}_2}}}$ = 0.209) and HYPO (FiO2${
Dania Ibrahim   +2 more
wiley   +1 more source

Correção da cifose de Scheuermann: estudo comparativo da fixação híbrida com ganchos e parafusos versus fixação apenas com parafusos Corrección de la cifosis de Scheuermann: estudio comparativo de la fijación híbrida con ganchos y tornillos versus fijación solo con tornillos Correction of Scheuermann kyphosis: comparative study of hybrid fixation using hooks and screws versus screw-only fixation

open access: yesColuna/Columna, 2009
OBJETIVOS: avaliar o grau de correção da cifose de Scheuermann, em 6 pacientes que se submeteram à instrumentação híbrida composta por ganchos e parafusos (H) e 17 fixados apenas com parafusos (P).
Enguer Beraldo Garcia   +6 more
doaj   +1 more source

VectorBase: improvements to a bioinformatics resource for invertebrate vector genomics. [PDF]

open access: yes, 2011
VectorBase (http://www.vectorbase.org) is a NIAID-supported bioinformatics resource for invertebrate vectors of human pathogens. It hosts data for nine genomes: mosquitoes (three Anopheles gambiae genomes, Aedes aegypti and Culex quinquefasciatus), tick (
Campbell, David   +13 more
core   +5 more sources

Simulating Federated Learning to Enable Multi‐Hospital Collaboration for Lumbopelvic Alignment Estimation

open access: yesJOR SPINE, Volume 8, Issue 4, December 2025.
Federated learning (FL) effectively estimates lumbopelvic parameters from multi‐center spinal imaging, matching centralized methods' accuracy while preserving patient privacy, highlighting FL's potential to enhance diagnostic precision and broaden AI‐driven clinical applications in spine care without compromising data confidentiality.
Andrea Cina   +12 more
wiley   +1 more source

High‐throughput classification and quantification of skinning phenotype in sweet potatoes

open access: yesThe Plant Phenome Journal, Volume 8, Issue 1, December 2025.
Abstract Sweet potatoes (SPs) (Ipomoea batatas) are a valued crop for their color, flavor, and nutrition. Harvesting is labor‐intensive, requiring hand‐picking to maintain skin quality. Mechanical harvesting often causes skin damage, known as “skinning,” where skin is cut, scraped, or torn, leading to lower quality during packing.
Zachary A. Bloom   +5 more
wiley   +1 more source

Federico di Montefeltro's hyperkyphosis: a visual-historical case report

open access: yesJournal of Medical Case Reports, 2008
Introduction The literature contains several publications describing the use of visual arts to develop observational skills in medical students. Portraits of individuals of the Italian Renaissance can be used to enhance these skills and stimulate the ...
D'Antoni Anthony V, Terzulli Stephanie L
doaj   +1 more source

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