Results 201 to 210 of about 4,881,160 (251)

Illuminating point‐of‐care diagnostics with aggregation‐induced emission biosensors

open access: yesFlexMat, EarlyView.
This review highlights the application of aggregation‐induced emission luminogens (AIEgens) in point‐of‐care (POC) diagnostics for disease biomarker detection. It systematically examines a range of biosensing platforms, including lateral flow immunoassays, microfluidic chips, and electrochemiluminescence sensors, alongside their utility in detecting ...
Danni Hu   +3 more
wiley   +1 more source

Flexible photocatalytic materials: From substrate engineering to multi‐field synergistic enhancement

open access: yesFlexMat, EarlyView.
This review examines flexible photocatalytic systems, covering substrate evolution from polymers to biomass, fabrication methods like electrospinning, and key mechanical and optoelectrochemical metrics under deformation. Enhancement strategies are critically discussed, followed by applications in energy conversion, environmental remediation, and ...
Weiqi Wang   +3 more
wiley   +1 more source

Biosensors for Food Safety and Adulteration Monitoring: Applications, Smart Packaging Integration, and Pathways to Intelligent, Field‐Deployable Detection Systems

open access: yesFood Safety and Health, EarlyView.
Biosensors enable rapid, sensitive, and portable detection of pathogens, contaminants, allergens, and food adulteration. Integration with smart packaging, smartphones, IoT, and machine learning supports real‐time monitoring and intelligent decision‐making, whereas microfluidics, biodegradable materials, explainable AI, and blockchain offer pathways ...
Mohima Akther Any   +7 more
wiley   +1 more source

Organ‐Resolved Host Proteomic and Post‐Translational Modification Landscapes in a Mouse Model of Talaromyces marneffei Infection

open access: yesiMetaMed, EarlyView.
We presented an organ‐resolved, multiple PTM remodeling atlas of systemic T. marneffei infection, integrating quantitative proteome, phosphoproteome, ubiquitinome, acetylome, and lactylome data across the liver, lung, and spleen. The atlas delineated organ‐specific PTM signatures and a functional convergence of divergent modification types on immune ...
Wudi Wei   +16 more
wiley   +1 more source

Mixed lineage kinase 3 mediates SARS‐CoV‐2‐induced kidney injury via the Hsp70‐IL‐17A axis

open access: yesInterdisciplinary Medicine, EarlyView.
Kidney samples from patients infected with severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) showed upregulated expression and activity of Mixed Lineage Kinase (MLK3). Based on the mechanistic studies, we identified MLK3 as a critical player in promoting SARS‐CoV‐2‐induced kidney injury.
Sandeep Kumar   +18 more
wiley   +1 more source

Synthesis, Cytotoxicity, and Apoptosis‐Associated Cell Death Activity of an Isatin‐Containing Pyrimidine‐Derived Cu(II) Complex

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT A Cu(II) complex derived from a pyrimidine with the isatin group was synthesized and tested for its cytotoxic effects on A549 lung cancer and MCF‐7 breast cancer cell lines, as well as its effects on apoptosis‐associated cell death and cell cycle regulation in A549 cells. To evaluate cytotoxicity, MTT assays were performed at 24, 48, and 72 h,
Müjgan Kesik Oktay   +4 more
wiley   +1 more source

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