Results 201 to 210 of about 14,342 (263)

Human Umbilical Cord Mesenchymal Stem Cell–Derived Exosomes Attenuate Renal Fibrosis by Suppressing Fibroblast Activation via the INHBA/PI3K/AKT Pathway

Pediatric Discovery, EarlyView.
MSC‐Exo derived from human umbilical cord (HucMSC‐Exo) downregulates INHBA expression, consequently modulating the PI3K/AKT signaling cascade. This regulation attenuates renal fibroblast activation and extracellular matrix deposition, thereby exerting a renoprotective effect against fibrosis.
Meiling Chen, Chenxi Jia, Zhuocheng Shi, Bianan Zhu, Yihang Yu, Xing Liu, Feng Liu, Jianwei Chen, Tao Xu, Yuanyuan Zhang, Deying Zhang, Guanghui Wei   +11 more
wiley   +1 more source

Tailored for Binding: Alanine‐Modified Poly(1‐Naphthylamine) Targets Serum Albumins

Polymer Engineering &Science, EarlyView.
Alanine modified poly(1‐naphthylamine). ABSTRACT This study presents a new approach for modifying the structural and functional properties of poly(1‐naphthylamine) (PNA) by incorporating the amino acid alanine (Ala) in different molar proportions (80/20, 50/50, and 20/80 for PNA/Ala) through an ultrasound‐assisted polymerization process.
Nuzhat Nabi, Ufana Riaz
wiley   +1 more source

Schiff based derived homogeneous catalysts for ring‐opening terpolymerization

Polymer International, EarlyView.
One‐pot synthesis of degradable terpolymers from l‐lactide, propylene oxide and CO₂ using diverse catalysts is described, revealing structure–property relationships for tailored applications in sustainable materials. Abstract In this study, we synthesized and evaluated a series of Schiff base cobalt catalysts for the terpolymerization of propylene ...
Akanksha Ranade, Amjad Ali, Rajeev Mehta
wiley   +1 more source

Advances in conjugated porous polymers via high internal phase emulsion templating

Polymer International, EarlyView.
This mini‐review highlights the design, synthesis and potential applications of π‐conjugated polyHIPEs, emphasizing their unique hierarchical structure and tunable properties. The work outlines innovative synthetic strategies and explores their promising roles in photocatalysis and environmental remediation, paving the way for future advancements in ...
Julie‐Lisa Malaval, Michel Granier, Philippe Gerbier, Sébastien Richeter, Sébastien Clément   +4 more
wiley   +1 more source

Betulinic Acid Enema Alleviates Colitis by Targeting Vitamin D Receptor to Protect the Intestinal Mucosal Barrier and Modulate Mucosa‐Associated Microbiota

Phytotherapy Research, EarlyView.
ABSTRACT Ulcerative colitis (UC) is a chronic inflammatory disease of the colon with limited effectiveness and safety of current drug therapies. Betulinic acid (BA) is a naturally occurring pentacyclic triterpenoid present in traditional Chinese medicines used clinically as retention enemas for UC, but its direct effects and mechanisms remain unclear ...
Lina Dong, Yuanxia Gao, Qian Li, Guangxin Chen, Dong Yang, Liping Zhao, Xiaojing Liu, Shumei Lin   +7 more
wiley   +1 more source

Machine learning‐driven advances in carbon‐based quantum dots: Opportunities accompanied by challenges

Responsive Materials, EarlyView.
Machine learning provides a unifying framework to connect structure, fluorescence properties, and applications of carbon‐based quantum dots. This review highlights how data‐driven strategies enable fluorescence regulation, reveal underlying mechanisms, and accelerate the rational design of functional carbon dots.
Liangfeng Chen, Siwei Yang, Xiangqian Cui, Ziheng Liu, Hang Wang, Yongqiang Li, Peng He, Miao Wang, Guqiao Ding   +8 more
wiley   +1 more source

Antimicrobial efficacies and molecular 3D modeling of novel biopolymer derivatives extracted from biowaste using a solid-state mechanochemical technique. [PDF]

RSC Adv
Manimohan M, Aboobucker Sithique M, Pugalmani S.   +2 more
europepmc   +1 more source

Antimicrobial, antibiofilm, antioxidant activities and molecular docking of Schiff base and its complexes of Cu(II), Co(II), Ni(II), Mn(II) and UO₂(II). [PDF]

Sci Rep
Wahba RH, AbouElleef EM, Gomaa EA, Diab MA, Abou-Dobara MI, El-Zahed MM, El-Sonbati AZ.   +6 more
europepmc   +1 more source

Synthesis, calf thymus DNA binding, in-vitro cytotoxicity, molecular docking, and antimicrobial studies of novel metal complexes containing a 2,3-diaminopyridine derivative Schiff base. [PDF]

Sci Rep
Helal MA, Shoaib RMS, El-Sonbati AZ, Diab MA, El-Mogazy MA, El-Zahed MM, Morgan SM.   +6 more
europepmc   +1 more source

Clobazam to preserve meaningful engagement in prolonged disorder of consciousness with concurrent seizure disorder

PM&R, EarlyView.
Tatiana Bernstein, Zachary Miklja, Tiffany Wood, Joshua Startup   +3 more
wiley   +1 more source