Results 201 to 210 of about 969,948 (286)

Localized Prostate Cancer Therapy: Tumor Microenvironment‐Activated Spermine Hydrogel With Real‐Time Autonomous Fluorescence Sensing

open access: yesChemistry – A European Journal, EarlyView.
First tumor microenvironment (TME)‐responsive spermine‐loaded hydrogel with autonomous sensing for advanced local therapy of prostate cancer (PCa) is developed. Spermine can be released from the hydrogel to kill the prostate cancer cells specifically under acidic TME.
Ho‐Fai Chau   +12 more
wiley   +1 more source

Organoselenium-based Schiff bases and amidic acid derivatives as promising anticancer agents targeting breast cancer by downregulating BCL-2: design, synthesis, and biological evaluation. [PDF]

open access: yesRSC Adv
Shaaban S   +11 more
europepmc   +1 more source

Turning Bonding Into Function: The Emerging Role of the Bioactive Selenium─Metal Motif in Toxicology and Medicinal Chemistry

open access: yesChemistry – A European Journal, EarlyView.
Balancing Act: Se─M bond serving as the fulcrum of the balance scale to compare the different weight of toxicity and therapeutic effects in biological environment. ABSTRACT The synthesis and characterization of organo‐selenium compounds have attracted considerable interest for decades, driven by the search for efficient catalysts and bioinspired ...
Matteo Filippi   +6 more
wiley   +1 more source

Spatiotemporal cellular dynamics of the notochord shape intervertebral disc morphogenesis in the mouse embryo through apoptosis and proliferation

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The notochord is a midline structure essential for vertebrate embryogenesis, contributing to the development of the nervous system, digestive tract, and vertebral column. In particular, notochord signaling is indispensable for proper patterning and coordinated development of alternating vertebrae and intervertebral discs (IVDs ...
Julie Warin   +5 more
wiley   +1 more source

Polyoxometalates in Photocatalytic CO2 Reduction: Multielectron Redox Regulation Across Molecular and Hybrid Architectures

open access: yesEcoEnergy, EarlyView.
This review focuses on multielectron redox regulation across molecular and hybrid architectures for photocatalytic CO2 reduction, covering intrinsic POM photocatalysts, photosensitizer‐assisted assemblies, POM–metal–organic complexes, and POM‐integrated semiconductors and MOF/COF heterostructures to link structural motifs with charge transport, product
Bonan Li, Xiaowen Ruan, Sai Kishore Ravi
wiley   +1 more source

Molecular‐Level Modulation of Proton Transport via Electron‐Proton Coupling in Bio‐p‐n Junctions

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
We developed a pH‐sensing device capable of operating in biological environments. A biohybrid p–n junction was constructed using bacteriorhodopsin (bR) and the photoconductive polymer poly(3‐hexylthiophene) (P3HT). Under light illumination, the photocurrent exhibits distinct transitions across various pH gradients, demonstrating the system's high ...
Chen Song   +7 more
wiley   +1 more source

Constructing Interface‐Enhanced S‐Heterojunctions Via Surface Functionalization Strategies to Improve Photocatalytic Hydrogen Production Efficiency in Inorganic/Organic Composite Systems

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
A surface in situ growth strategy was employed to fabricate a COF/TiO2 S‐scheme heterojunction with enhanced interfacial forces. This enhanced interfacial heterojunction significantly improved photocatalytic hydrogen production capacity. S‐scheme heterojunctions play a crucial role in enhancing charge‐carrier separation efficiency and redox capability.
Xinhui Jiang   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy