Results 31 to 40 of about 61,070 (300)

Discovery of New Schiff Bases Tethered Pyrazole Moiety: Design, Synthesis, Biological Evaluation, and Molecular Docking Study as Dual Targeting DHFR/DNA Gyrase Inhibitors with Immunomodulatory Activity

Molecules, 2020
A series of Bis-pyrazole Schiff bases (6a–d and 7a–d) and mono-pyrazole Schiff bases (8a–d and 9a–d) were designed and synthesized through the reaction of 5-aminopyrazoles 1a–d with aldehydes 2–5 using mild reaction condition with a good yield percentage.
Ashraf S. Hassan, Ahmed A. Askar, Ahmed M. Naglah, Abdulrahman A. Almehizia, Ahmed Ragab   +4 more
doaj   +1 more source

Coordination chemistry and bioactivity of Ni2+, Cu2+, Cd2+ and Zn2+ complexes containing bidentate schiff bases derived from S-benzyldithiocarbazate and the X-ray crystal structure of bis[S-benzyl-β-N-(5-methyl-2-furylmethylene)dithiocarbazato]cadmium(II). [PDF]

, 2002
New bidentate isomeric NS and NS′ Schiff bases were derived from the condensation of S-benzyldithiocarbazate (SBDTC) with 5-methyl-2-furyldehyde and 2-furyl-methylketone.
Ali, A.M., Crouse, Karen Anne, Fun, H.K., Khoo, Teng Jin, Tarafder, Md. Tofazzal Hossain, Yamin, B.M.   +5 more
core   +1 more source

Exploring the Potential Biological Activities of Pyrazole-Based Schiff Bases as Anti-Diabetic, Anti-Alzheimer’s, Anti-Inflammatory, and Cytotoxic Agents: In Vitro Studies with Computational Predictions

Pharmaceuticals
In this innovative research, we aim to reveal pyrazole-based Schiff bases as new multi-target agents. In this context, we re-synthesized three sets of pyrazole-based Schiff bases, 5a–f, 6a–f, and 7a–f, to evaluate their biological applications.
Ahmed M. Naglah, Abdulrahman A. Almehizia, Asma S. Al-Wasidi, Amirah Senaitan Alharbi, Mohammed H. Alqarni, Ashraf S. Hassan, Wael M. Aboulthana   +6 more
doaj   +1 more source

Manganese Schiff Base Complexes, Crystallographic Studies, Anticancer Activities, and Molecular Docking

Journal of Chemistry, 2022
Choice of ligands is significant to successful synthesis of metal complexes (coordination compounds). This study reports the use of Schiff base as the right ligand to control the poor bioavailability and neurodegenerative toxicity challenges of manganese
Ayodele Temidayo Odularu
doaj   +1 more source

Novel Schiff Bases of C-Methylresorcinarene Derivatives

Molbank, 2022
The article presents the synthesis and properties of two new Schiff bases of resorcinarene derivatives. The Schiff bases were obtained by the reaction of formylresorcinarene with aromatic (o-aminophenol) and aliphatic (N,N-dimethyldiaminoethane) amines ...
Albina Y. Ziganshina, Olga S. Saranova, Rezeda R. Fazleeva, Vitaly V. Yanilkin, Igor S. Antipin   +4 more
doaj   +1 more source

The Morphology and Performance of Poly(Vinyl Chloride) Containing Melamine Schiff Bases against Ultraviolet Light

Molecules, 2019
Five Schiff bases derived from melamine have been used as efficient additives to reduce the process of photodegradation of poly(vinyl chloride) films. The performance of Schiff bases has been investigated using various techniques.
Gamal A. El-Hiti, Mohammad Hayal Alotaibi, Ahmed A. Ahmed, Basheer A. Hamad, Dina S. Ahmed, Ahmed Ahmed, Hassan Hashim, Emad Yousif   +7 more
doaj   +1 more source

Amino-Acid-Derived Oxazolidin-5-Ones as Chemical Markers for Schiff Base Formation in Glycation Reactions

Applied Sciences, 2023
Imine or Schiff base formation is considered as a key event in the catalytic mechanisms of many enzymes and in certain biological transformations, including glycation.
Eun Sil Kim, Varoujan Yaylayan
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Synthesis and characterization of Novel Schiff bases and evaluation of Corrosion inhibitors and biological activity

مجلة علوم ذي قار, 2019
Novel Schiff bases have been prepared from (6R,7R)-3-[( acetyloxy)methyl]-7-[[( Z)-2-(2aminothiazol-4-yl)-2-(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]-oct-2-ene-2carboxylate sodium and 2,4-dihydroxy benzaldehyde ,3-methoxy-4-hydroxy
Ahmed M. Jassim
doaj   +4 more sources

Synthesis, Characterization, and Molecular Docking Studies of Fluoro and Chlorophenylhydrazine Schiff Bases

Journal of the Turkish Chemical Society, Section A: Chemistry, 2019
Six Schiff bases synthesized by condensation reaction of p-fluoro and chlorophenylhydrazines with some carbonyl compounds were reported in this work. Structures of the prepared compounds were elucidated by FT-IR, 1H- and 13C-NMR spectroscopy.
Ayşegül Şenocak
doaj   +1 more source