Results 31 to 40 of about 27,347 (176)

Development of an in vitro drug screening assay using Schistosoma haematobium schistosomula [PDF]

, 2012
BACKGROUND: The development of novel antischistosomal drugs is crucial, as currently no vaccine and only a single drug is available for the treatment of schistosomiasis.
Ingram, K., Katrin Ingram, Marxer Monika, Marxer, Monika, Jennifer Keiser, Ingram Katrin, Keiser Jennifer, Keiser, Jennifer, Marxer, M., Keiser, J., Monika Marxer, Ingram, Katrin   +11 more
core   +1 more source

CD4+ T-cell counts, CD4+/CD8+ T-cell count ratios, and antibody levels in migrant fishermen infected with Schistosoma japonicum in the Dongting Lake, China. [PDF]

, 2006
In this study, CD4(+) and CD8(+) T cells and antibody levels were measured in 94 migrant fishermen infected with Schistosoma japonicum from Dongting Lake, China. Prevalence among these fishermen was high (63.8%), with a mean infection intensity of 61.4 +/
McManus, Donald P., Li, Yuesheng, Zeng, Qinren, Xiong, Tie, Ellis, Magda K, Balen, Julie, McManus, Donald P, Ellis, Magda K.   +7 more
core   +1 more source

Reconstructing colonization dynamics of the human parasite Schistosoma mansoni following anthropogenic environmental changes in northwest Senegal [PDF]

, 2015
Schistosoma parasites successfully colonize new regions following the construction of water schemes for power production or agricultural purposes. Here we investigated the colonization history of the human parasite Schistosoma mansoni in Northwest ...
Maarten H D Larmuseau, Sy Ibrahima, Polman, K, Djibril Faye, Volckaert, Filip, Ibrahima Sy, Huyse, Tine, David Rollinson, Polman, K., Maes, GE, Tine Huyse (370703), Frederik Van den Broeck (3213429), Faye, D, Tine Huyse, Sy, I., Huyse Tine, Katja Polman, Faye, Djibril, Maes, G.E., Filip A M Volckaert, Volckaert Filip A. M., Maes, Gregory, Sy, Ibrahima, Polman, Katja, Van den Broeck Frederik, Djibril Faye (783672), Maes, Gregory E., Rollinson, D, Katja Polman (154672), Volckaert, FAM, Sy, I, David Rollinson (103447), Larmuseau, Maarten, Larmuseau, Maarten H.D., Rollinson, David, Maes Gregory E., Polman, K.; id_orcid, Volckaert, Filip A.M., Gregory E Maes, Huyse, T., Polman Katja, Maarten H. D. Larmuseau (655788), Ibrahima Sy (783671), Rollinson David, Huyse, T, Faye, D., Van den Broeck, Frederik, Faye Djibril, Filip A. M. Volckaert (218575), Rollinson, D., Larmuseau, M.H., Larmuseau, MHD, Frederik Van den Broeck, Larmuseau Maarten H. D., Van den Broeck, F., Gregory E. Maes (145256), Van den Broeck, F, Volckaert, F.A.   +57 more
core   +3 more sources

Praziquantel analogs with activity against juvenile Schistosoma mansoni.

, 2010
Six amide and four urea derivatives of praziquantel were synthesized and tested for antischistosomal activity against juvenile and adults stages of Schistosoma mansoni in infected mice. Only one of these had significant activity against adult worms, but,
Vennerstrom, Jonathan L, Bickle, Quentin, Bickle, Q., Chollet, Jacques, Keiser, J., Mansour, N. R., Alnouti, Yazen, Huang, Jiangeng, Vennerstrom, J. L., Mansour, Nuha R, Dong, Y., Keiser, Jennifer, Vargas, M., Dong, Yuxiang, Alnouti, Y., Vargas, Mireille, Chollet, J., Huang, J.   +17 more
core   +1 more source

Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on intensity of infection and antibody responses to schistosome antigens: results of a randomised, placebo-controlled trial. [PDF]

, 2009
BACKGROUND: Praziquantel treatment of schistosomiasis during pregnancy was only recommended in 2002; hence the effects of treatment during pregnancy are not fully known. We have therefore evaluated the effects on infection intensity and the immunological
Emojong Nicholas O, Dunne, David W., Mawa, Patrice A, Birgitte J Vennervald, Jones Frances M, Jones, Frances M., Duong, Trinh, Patrice A Mawa, Emojong, Nicholas O., Vennervald, Birgitte J, Mawa Patrice A, Frances M Jones, Alison M Elliott, Trinh Duong, Mpairwe Harriet, Elliott, Alison M, Robert Tweyongyere, Mawa, Patrice A., Mpairwe, Harriet, Emojong, Nicholas O, Dunne, David W, Katunguka-Rwakishaya Eli, Elliott Alison M, Tweyongyere, Robert, David W Dunne, Katunguka-Rwakishaya, Eli, Dunne David W, Elliott, Alison M., Duong Trinh, Vennervald Birgitte J, Nicholas O Emojong, Eli Katunguka-Rwakishaya, Tweyongyere Robert, Jones, Frances M, Harriet Mpairwe   +34 more
core   +1 more source

Peptide-Alkoxyamine Drugs: An Innovative Approach to Fight Schistosomiasis: “Digging Their Graves with Their Forks”

Pathogens
The expansion of drug resistant parasites sheds a serious concern on several neglected parasitic diseases. Our recent results on cancer led us to envision the use of peptide-alkoxyamines as a highly selective and efficient new drug against schistosome ...
Ange W. Embo-Ibouanga, Michel Nguyen, Jean-Patrick Joly, Mathilde Coustets, Jean-Michel Augereau, Lucie Paloque, Nicolas Vanthuyne, Raphaël Bikanga, Anne Robert, Françoise Benoit-Vical, Gérard Audran, Philippe Mellet, Jérôme Boissier, Sylvain R. A. Marque   +13 more
doaj   +1 more source

Protein tyrosine kinases in Schistosoma mansoni

Memorias do Instituto Oswaldo Cruz, 2006
The identification and description of signal transduction molecules and mechanisms are essential to elucidate Schistosoma mansoni host-parasite interactions and parasite biology.
Diana Bahia, Luiza Freire Andrade, Fernanda Ludolf, Renato Arruda Mortara, Guilherme Oliveira   +4 more
doaj   +1 more source

Praziquantel, mefloquine-praziquantel, and mefloquine-artesunate-praziquantel against Schistosoma haematobium : a randomized, exploratory, open-label trial [PDF]

, 2014
Treatment and morbidity control of schistosomiasis relies on a single drug, praziquantel. Hence, there is a pressing need to develop additional therapeutics against schistosomiasis.
Silué, Kigbafori D., Monsan, N'Chou, Jennifer Keiser, Eliézer K. N'Goran (108853), Utzinger, Jürg, Nicaise A. N'Guessan (195087), Nicaise A N'Guessan, Adiossan, Lukas K., Lukas K Adiossan, Jürg Utzinger (39609), N'Chou Monsan, Kigbafori D. Silué (128980), Eliézer K N'Goran, Keiser, Jennifer, N'Chou Monsan (599780), N'Goran, Eliézer K., Jennifer Keiser (39606), N'Guessan, Nicaise A., Kigbafori D Silué, Jürg Utzinger, Lukas K. Adiossan (599779)   +20 more
core   +1 more source

The Mannose Receptor in Regulation of Helminth-Mediated Host Immunity

Frontiers in Immunology, 2017
Infection with parasitic helminths affects humanity and animal welfare. Parasitic helminths have the capacity to modulate host immune responses to promote their survival in infected hosts, often for a long time leading to chronic infections.
Irma van Die, Richard D. Cummings
doaj   +1 more source

Evaluation of Loop-Mediated Isothermal Amplification (LAMP) in Urine Samples for the Diagnosis of Imported Schistosomiasis

Tropical Medicine and Infectious Disease, 2023
Migratory flows and international travel are triggering an increase in imported cases of schistosomiasis in non-endemic countries. The present study aims to evaluate the effectiveness of the LAMP technique on patients’ urine samples for the diagnosis of ...
Joaquín Salas-Coronas, María Pilar Luzón-García, Beatriz Crego-Vicente, Manuel Jesús Soriano-Pérez, Begoña Febrer-Sendra, José Vázquez-Villegas, Juan García-Bernalt Diego, Isabel María Cabeza-Barrera, Nerea Castillo-Fernández, Antonio Muro, María Dolores Bargues, Pedro Fernández-Soto   +11 more
doaj   +1 more source