Results 61 to 70 of about 29,527 (131)

Adaptation of Echinococcus Multilocularis to Oxidative Stress Depends on EmPDK‐Mediated Metabolic Reprogramming

Advanced Science, Volume 13, Issue 59, 23 October 2026.
Metabolic adaption presents a vital survival strategy for E. multilocularis. This study identifies EmPDK as a central metabolic regulator governing glucose metabolic reprogramming. Oxidative stress activates EmHIF1α to induce EmPDK expression. Mechanistic characterization reveals this ROS/EmHIF1α/EmPDK axis drives glycolytic reprogramming to sustain ...
Huijuan Wang, Zhijian Xu, Ye Tian, Yao Zhang, Zhe Cheng, Yanhai Wang   +5 more
wiley   +1 more source

Differences in the gene expression profiles of Haemocytes from Schistosome-susceptible and -resistant Biomphalaria glabrata exposed to Schistosoma mansoni excretory-secretory products [PDF]

, 2014
During its life cycle, the helminth parasite Schistosoma mansoni uses the freshwater snail Biomphalaria glabrata as an intermediate host to reproduce asexually generating cercariae for infection of the human definitive host.
Rollinson, D, Kirk, Ruth S, Catherine S. Jones (107541), Davies, Angela J, Angela J. Davies (103446), David Rollinson (103447), Aidan M Emery, David Rollinson, Rollinson, David, Leslie R Noble, Lockyer, AE, Kirk, RS, Lockyer Anne E., Anne E. Lockyer (107520), Ruth S Kirk, Davies Angela J., Kirk, Ruth, Jones Catherine S., Noble, Leslie R, Jones, Catherine S, Noble, LR, Ruth S. Kirk (541547), Catherine S Jones, Anne E Lockyer, Rollinson David, Walker, Anthony J., Jones, CS, Walker Anthony J., Walker, AJ, Zahoor Zahida, Leslie R. Noble (107538), Aidan M. Emery (103448), Emery, AM, Anthony J Walker, Emery, Aidan M, Walker, Anthony J, Davies, AJ, Zahoor, Zahida, Lockyer, Anne E, Zahida Zahoor, Anthony J. Walker (103449), Noble Leslie R., Zahoor, Z, Angela J Davies, Emery Aidan M., Zahida Zahoor (541546), Kirk Ruth S.   +46 more
core   +2 more sources

Comparativo e perfil dos infectados em esquistossomose no estado de Alagoas entre 2016 e 2017

Pubvet, 2019
A esquistossomose é uma doença parasitária causada por protozoário que tem como habitat rios, riachos e açudes que são comuns em Alagoas. Esse artigo visa analisar casos confirmados da esquistossomose em Alagoas e o perfil epidemiológico dos infectados ...
Carlos Miguel Azarias dos Santos, Lyara Suzhanny de Oliveira Santos, Jeffeson Araújo dos Santos, Erilza dos Santos Silva, Maria Hilma dos Santos, Dayane Kelly Da Silva, Josicleide Fernandes de Souza Santos, Douglas de Oliveira Subrinho, Cristiane Kelly Aquino dos Santos, Claudimary Bispo dos Santos   +9 more
doaj   +1 more source

Huge Colonic Granuloma of Schistosomiasis Mimicked Cancer in a 10-Years-Old Child: A Case Report

International Medical Case Reports Journal, 2022
Qasem Alyhari,1 Faisal Ahmed,2 Hani Al_Shaibani,3 Mohammed Al_Kubati,4 Assad Alhadi5 1Department of General Surgery, School of Medicine, Ibb University of Medical Sciences, Ibb, Yemen; 2Urology Research Center, Al-Thora General Hospital, Department of ...
Alyhari Q, Ahmed F, Al_Shaibani H, Al_Kubati M, Alhadi A   +4 more
doaj  

Development of a laboratorial platform for diagnosis of schistosomiasis mansoni by PCR-ELISA

BMC Research Notes, 2018
Objective We developed a laboratorial platform to release a commercial platform used in the PCR-ELISA for the molecular diagnosis of schistosomiasis mansoni.
Carolina Senra, Luciana Inácia Gomes, Liliane Maria Vidal Siqueira, Paulo Marcos Zech Coelho, Ana Rabello, Edward Oliveira   +5 more
doaj   +1 more source

Parasite‐Derived IL‐33 Inhibitors Prevent Bleomycin‐Induced Lung Fibrosis

European Journal of Immunology, Volume 56, Issue 10, October 2026.
Infection with the intestinal helminth Heligmosomoides polygyrus bakeri, or administration of the parasite products (HES), or administration of recombinant HpARI2+HpBARI_Hom2 can all suppress the development of lung fibrosis in the mouse bleomycin model, via suppression of the IL‐33 pathway. Graphic abstract created in BioRender. McSorley, HJ.
Samuele Di Carmine, Tania Frangova, Suzanne H. Hodge, Danielle J. Smyth, Tera Birchall, Josh Richards, Ian Newton, Sarah Kelly, Alice R. Savage, E. Suzanne Cohen, J. Simon C. Arthur, Henry J. McSorley   +11 more
wiley   +1 more source

Peptide-Alkoxyamine Drugs: An Innovative Approach to Fight Schistosomiasis: “Digging Their Graves with Their Forks”

Pathogens
The expansion of drug resistant parasites sheds a serious concern on several neglected parasitic diseases. Our recent results on cancer led us to envision the use of peptide-alkoxyamines as a highly selective and efficient new drug against schistosome ...
Ange W. Embo-Ibouanga, Michel Nguyen, Jean-Patrick Joly, Mathilde Coustets, Jean-Michel Augereau, Lucie Paloque, Nicolas Vanthuyne, Raphaël Bikanga, Anne Robert, Françoise Benoit-Vical, Gérard Audran, Philippe Mellet, Jérôme Boissier, Sylvain R. A. Marque   +13 more
doaj   +1 more source

Testicular schistosomiasis mimicking tumour

International Brazilian Journal of Urology, 2004
Schistosomiasis or bilharziasis is a disease caused by Schistosoma. When infecting men the most common parasites are Schistosoma mansoni, Schistosoma japonicum and Schistosoma haematobium.
Nicola Mortati Neto, João P. S. Grando, Horacio A. Moreira   +2 more
doaj   +1 more source

Mucosal‐Associated Invariant T Cells in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao, Feng‐Mi Ou, Dan Liang, Yang Gao, Qing‐Qing Li, Yi‐Qun Kuang   +5 more
wiley   +1 more source

Fluorescence/luminescence-based markers for the assessment of Schistosoma mansoni schistosomula drug assays [PDF]

, 2015
Schistosomiasis is responsible for a tremendous public health burden, yet only a single drug, praziquantel, is available. New antischistosomal treatments should therefore be developed. The accuracy, speed and objectivity of in vitro drug screening depend
Gordana Panic, Jennifer Keiser, Flores, Dayana, Keiser, Jennifer, Ingram-Sieber, Katrin, Dayana Flores, Katrin Ingram-Sieber, Panic, Gordana, Keiser J, Flores D, Panic G, Ingram-Sieber K   +11 more
core   +1 more source